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Krebs Edwin G: more detail

The Enzymes: Control by Phosphorylation, Part B : Specific Enzymes by Paul D. Boyer, 1987-03

Protein Phosphorylation/Vol 8 Books A and B (CSH Conferences on Cell Proliferation) by Ora M. Rosen, Edwin G. Krebs, 1981-08-01

An Accidental Biochemist (Annual Review of Biochemistry) by Edwin G. Krebs, 1998-07-01

Intracellular Signal Transduction, Volume 36 (Advances in Pharmacology) (v. 36)

The Enzymes: Control by Phosphorylation, Part A : General Features, Specific Enzymes by Paul D. Boyer, 1986-11

People From Bond County, Illinois: Gretchen Wilson, Edwin G. Krebs, Ron Stephens, Frank Watson, Phyllis Holmes, Robert Smith, Job Adams Cooper

Protein Phosphorylation Book A Cell Proliferation volume 8 by Ora M.; Krebs, Edwin G. Rosen, 1981-01-01

lists with details

Edwin G. Krebs Winner Of The 1992 Nobel Prize In Medicine
edwin G. krebs, a nobel Prize Laureate in Physiology and Medicine, at the nobelPrize Internet Archive. edwin G. krebs. 1992 nobel Laureate in Medicine
http://almaz.com/nobel/medicine/1992b.html
Index Of Nobel Laureates In Medicine
ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE. Name,Year Awarded. Kornberg, Arthur, 1959. Kossel, Albrecht, 1910. krebs, edwin G. 1992.
http://almaz.com/nobel/medicine/alpha.html
Edwin G. Krebs - Autobiography
edwin G. krebs Autobiography. June 6, 1918, the third of the four children ofWilliam Carl krebs and Louise Helen (Stegeman) krebs. From Les Prix nobel 1992
http://www.nobel.se/medicine/laureates/1992/krebs-autobio.html

Extractions: During my fourth year at the University of Illinois I carried out undergraduate research in organic chemistry and found it to be a fascinating experience. This was probably the first time that I had ever taken a "course" that seemed like fun. Because I was ahead in my credits, I was able to spend virtually unlimited time in the laboratory. My mentors were Harold Snyder and Charles Price, and to them I will always be grateful for having introduced me to research. Another influential teacher during this period was Carl S. Marvel. Had this research experience come earlier in my college career, I might well have opted for a Ph.D. in organic chemistry rather than going to medical school. But as it turned out, this introduction to research influenced my medical training and without doubt was a strong factor in my eventually becoming a research biochemist rather than a clinician. Washington University School of Medicine proved to be an excellent choice as a place where I could receive classical medical training but at the same time learn to appreciate "medical research." The basic science courses were the equivalent of graduate courses and there was no attempt to water down the curriculum based on the idea that physicians only need "core" knowledge in the various sciences. In addition to basic course work that took us to the fringes of knowledge in the various disciplines, students were encouraged to participate in laboratory projects. I personally undertook several projects, first under Dean Philip A. Schafer, who was also chairman of the Department of Biochemistry, and later under Arda A. Green, a faculty member associated with Dr.
Edwin G. Krebs - Nobel Lecture
edwin G. krebs nobel Lecture. Protein phosphorylation and cellularregulation, I. edwin G. krebs Autobiography nobel Lecture. 1991, 1993.
http://www.nobel.se/medicine/laureates/1992/krebs-lecture.html
Krebs, Edwin Gerhard
krebs, edwin Gerhard. (b. June 6, 1918, Lansing, Iowa, US), American biochemist,winner with Edmond H. Fischer of the 1992 nobel Prize for Physiology or Medicine
http://www.britannica.com/nobel/micro/329_3.html

Extractions: (b. June 6, 1918, Lansing, Iowa, U.S.), American biochemist, winner with Edmond H. Fischer of the 1992 Nobel Prize for Physiology or Medicine . They discovered reversible protein phosphorylation, a biochemical process that regulates the activities of proteins in cells and thus governs countless processes that are necessary for life. Krebs received a medical degree from Washington University (St. Louis, Mo.) in 1943. From 1946 to 1948 he did research there under the biochemists Carl and Gerty Cori. In 1948 he joined the faculty of biochemistry at the University of Washington, Seattle, becoming full professor in 1957. In 1968 he moved to the University of California at Davis, returning to Washington University in 1977. During the 1950s Krebs and Edmond Fischer began investigating the process by which muscle cells obtain energy from glycogen (the form in which the body stores sugar). The Coris had previously demonstrated that cells use an enzyme called phosphorylase to release glucose (the source of energy in cell function) from glycogen. Krebs and Fischer showed that phosphorylase could be converted from an inactive to an active form by the addition of a phosphate group taken from the compound adenosine triphosphate (ATP). The enzymes that catalyze this process are called protein kinases. Krebs and Fischer also showed that phosphorylase is inactivated by the removal of a phosphate group; this process is catalyzed by enzymes called phosphatases. Malfunctions in protein phosphorylation have been implicated in the causation of diseases such as diabetes, cancer, and Alzheimer's disease.
Nobel Prize Winners For 1991-Present
physiology/medicine, krebs, edwin Gerhard, US, discovery of class of enzymes called physics,Shull, Clifford G. US, development of neutronscattering techniques,
http://www.britannica.com/nobel/1991_pres.html

Extractions: Year Category Article Country* Achievement Literary Area chemistry Ernst, Richard R. Switzerland improvements in nuclear magnetic resonance spectroscopy economic science Coase, Ronald U.S. application of economic principles to the study of law literature Gordimer, Nadine South Africa novelist peace Aung San Suu Kyi Myanmar physics Gennes, Pierre-Gilles de France discovery of general rules for behaviour of molecules physiology/medicine Neher, Erwin Germany discovery of how cells communicate, as related to diseases physiology/medicine Sakmann, Bert Germany discovery of how cells communicate, as related to diseases chemistry Marcus, Rudolph A. U.S. explanation of how electrons transfer between molecules economics Becker, Gary S. U.S. application of economic theory to social sciences literature Walcott, Derek St. Lucia poet peace Guatemala physics Charpak, Georges France inventor of detector that traces subatomic particles physiology/medicine Fischer, Edmond H. U.S. discovery of class of enzymes called protein kinases physiology/medicine Krebs, Edwin Gerhard
UW Dept Of Pharmacology--Dr. Edwin G. Krebs
Box 357370 Seattle WA 981957370 Phone (206) 543-8500; Fax (206) 685-9720 egkrebs@u.washington.edu1992 nobel Prize Winners The edwin G. krebs Lectureship in
http://depts.washington.edu/phcol/fac/krebs.html

Extractions: Emeritus Professor of Pharmacology and Biochemistry Protein Phosphorylation and Signaling This laboratory is concerned with the mechanisms involved in the intra-cellular transmission of hormone and growth factor signals. Of particular interest are mechanisms that involve the phosphorylation and dephosphorylation of proteins. One specific area of research addresses the question of how growth factor receptors possessing protein tyrosine kinase activity, e.g. the insulin, epidermal growth factor, and the platelet-derived growth factor receptors, regulate the phosphorylation of cellular proteins on serine or threonine residues. How is this latter category of protein phosphorylation/dephosphorylation related to changes in cell functions? The laboratory is also interested in the mechanisms that are involved in programmed cell death or apoptosis. Through identification of the specific protein kinases involved in apoptosis it is hoped that some light can be shed on this process. Publications Graves JD, Gotoh Y, Draves KE, Ambrose D, Chernoff J, Clark EA, and Krebs EG. (1998) Caspase-mediated activation and induction of apoptosis by the mammalian Ste-20-like kinase Mst1.
UW Dept Of Pharmacology--Introduction
The discovery of a regulatory mechanism affecting almost all cells led to Nobelhonors on October 12, 1992 for edwin G. krebs, Professor Emeritus of
http://depts.washington.edu/phcol/phc/nobel.html

Extractions: The discovery of a regulatory mechanism affecting almost all cells led to Nobel honors on October 12, 1992 for Edwin G. Krebs , Professor Emeritus of Pharmacology and Biochemistry, and Edmond H. Fischer, Professor Emeritus of Biochemistry. The winners of the 1992 Nobel Prize in Physiology or Medicine discovered a "life switch" that turns on and off a variety of biological functions in the cell, including the breakdown of fats and the generation of chemical energy. This prize-winning discovery is known as "reversible protein phosphorylation." This breakthrough, discovered at the UW and first published in 1956, has led to research into how glycogen in the body breaks down into glucose. It has also fostered techniques that prevent the body from rejecting transplanted organs. The discovery has opened new doors for research into cancer, blood pressure, inflammatory reactions and brain signals. Some believe the process could have a role in diabetes. In phosphorylation, cell proteins are altered to perform their duties as enzymes, catalysts, energy-transfer agents or other functinos. The protein is "switched on" when its shape is altered by the addition of one or more phosphate groups. When the phosphate group is taken away, the protein's work changes or stops.
Edwin Krebs
edwin G. krebs is a softspoken, understated Midwesterner, but They confuse himwith Sir HA krebs, the British scientist who won the nobel Prize in
http://www.washington.edu/alumni/columns/march98/krebs.html

Extractions: Edwin G. Krebs Edwin G. Krebs is a soft-spoken, understated Midwesterner, but there's one thing that gets his goat. Since he turned his attention from medicine to biochemistry, people have been asking him about "his" cycle. They confuse him with Sir H.A. Krebs, the British scientist who won the Nobel Prize in 1953 for elucidating the metabolic Krebs (or tricarboxylic acid) cycle. One person who made this mistake was the chairman of a clinical department at the UW School of Medicine in 1948, when Krebs started as an assistant professor of biochemistry. "I must confess that I didn't correct his wrong impression," says Krebs. "I was so uneasy about my status then that I enjoyed being treated with such deference, even for the wrong reason." In 1992, Krebs and Edmond H. Fischer were awarded the Nobel Prize in physiology or medicine for figuring out how reversible phosphorylation works as a switch to activate proteins and regulate various cellular processes. Their discovery was a key to unlocking how glycogen in the body breaks down into glucose. It fostered techniques that prevent the body from rejecting transplanted organs. Their breakthrough also opened new doors for research into cancer, blood pressure, inflammatory reactions and brain signals. "One of the things that went through my mind when we won was that I wouldn't have to answer that cycle question again," says Krebs. "But people still congratulate me for having `my' cycle recognizedand think it took till 1992 for that to happen."
Nobel Laureate
Edmond H. Fischer, Ph.D. 1992 nobel Prize Recipient in Physiology/Medicine.for his joint discovery with edwin G. krebs concerning reversible protein
http://www.cnsm.csulb.edu/nobel_laureate.htm

Extractions: 11am - Noon - General Lecture 4 - 5pm - Technical Lecture Edmond H. Fischer BIOGRAPHY Dr. Edmond H. Fischer was born in Shanghai in 1920. At age 7 he went to Switzerland where he carried out all his studies, receiving B.S. degrees in chemistry and biology and a Ph.D. degree in organic chemistry from the University of Geneva. After a few years as a Fellow of the Rockefeller Foundation and a Privat Docent at the University of Geneva, he spent a year at the California Institute of Technology. In 1953, he joined the Department of Biochemistry at the University of Washington, where he is now Professor Emeritus.
The Scientist - Citation Records Underscore Nobel Winners' Long-Standing Influen
The publishing duo of edwin G. krebs and Edmond H. Fischer it, his work in associationwith krebs has been and often mentioned as deserving of a nobel Prize.
http://www.the-scientist.com/yr1992/dec/veggeberg_p1_921207.html

Extractions: News By Scott Veggeberg Influence On Lab Research Date: December 7, 1992 For the scientists who won this year's Nobel prizes in chemistry and in physiology or medicine, a commanding citation record, as determined by the Philadelphia-based Institute for Scientific Information, was a clear indication that they were in the running for this most coveted award. The prize in physics, however, went to a French physicist at CERN whose citation history, although impressive, has not been nearly as meteoric as the other recipients. The chemistry prize was awarded to California Institute of Technology's Rudolph A. Marcus for his work in divining the mechanisms of electron-transfer reactions. His first major paper on the topic was published in 1956, with refinements and extensions added over the next nine years. This seminal paper, entitled "Theory of oxidation-reduction reactions involving electron-transfer" (R.A. Marcus, Journal of Chemical Physics, 24:966, 1956), has garnered more than 1,100 citations since its appearance, but the importance of this work was slow to be recognized. It was cited five times in 1957 and only twice during the next year. However, the number of citations has climbed steadily over the ensuing years, and peaked more than three decades after publicationwith nearly 120 citationsin 1991. His final paper in the series of work that led to the prize was published in 1965 and has so far been cited almost 1,000 times, and has had a similar slow and steady citational climb (R.A. Marcus, J. Chem. Phys., 43:679, 1965).
HistoryLink Database Output
On October 12, 1992, Edmond H. Fischer (b. 1920) and edwin G. krebs (b. 1918) ofthe University of Washington School of Medicine receive the nobel Prize for
http://www.historylink.org/_output.CFM?file_ID=3660
HistoryLink Database Search Results
Full Text . Title Edmond H. Fischer and edwin G. krebs receivethe nobel Prize for Medicine on October 12, 1992. Abstract On
http://www.historylink.org/_results.cfm?keyword=Most/Least&searchfield=topic
Nobel Prizes In Medicine And Physiology
nobel Prizes in Medicine and Physiology. USA) 1991 E. Neher (Germany) B. Sakmann(Germany) 1992 Edmond H. Fischer (USA, *1920) edwin G. krebs (USA, *1918
http://userpage.chemie.fu-berlin.de/diverse/bib/nobel_medizin_e.html

Extractions: (List, not checked) E. A. v. Behring (Germany) Sir R. Ross (United Kingdom) N. R. Finsen (Denmark) I. P. Pawlow (Russia) R. Koch (Germany) C. Golgi (Italy) (Spain) Ch. L. A. Laveran (France) P. Ehrlich (Germany) I. Metschnikow (France, Russia) Th. Kocher (Switzerland) A. Kassel (Germany) A. Gullstrand (Sweden) A. Carrel (USA, France) Ch. Richet (France) (Austria) J. Bordet (Belgium) A. Krogh (Denmark) A. V. Hill (United Kingdom) O. Meyerhof (Germany) F. G. Banting (Canada) J. J. R. Macleod (Canada) W. Einthoven (Netherlands) J. Fibiger (Denmark) J. Wagner-Jauregg (Austria) Ch. Nicolle (France) Chr. Eijkman (Netherlands) Sir F.G. Hopkins (United Kingdom) K. Landsteiner (USA, Austria) O. H. Warburg (Germany) Ch. S. Sherrington (United Kingdom) E.D. Adrian (United Kingdom) Th. H. Morgan (USA) G. R. Minot (USA) W. P. Murphy (USA) G.H. Whipple (USA) H. Spemann (Germany) Sir H.H. Dale (United Kingdom) Otto Loewi (Austria, 1873-06-03 - 1961-12-25) (Hungary) C. Heymans (Belgium) G. Domagk
Premios Nobel De Medicina
Premios nobel de Medicina. con la fosforilación reversible de las proteínas comoun mecanismo de regulación biológica , Fischer, Edmond H.; krebs, edwin G.
http://fai.unne.edu.ar/biologia/nobeles/nobelmed.htm

Extractions: Premios Nobel de Medicina Tema Ganador Behring, Emil Adolf Von Ross, Sir Ronald Finsen, Niels Ryberg Pavlov, Ivan Petrovich Koch, Robert Cajal, Santiago Ramon Y.; Golgi, Camillo Laveran, Charles Louis Alphonse Ehrlich, Paul; Metchnikoff, Ilya Ilyich Kocher, Emil Theodor Kossel, Albrecht Gullstrand, Allvar Carrel, Alexis Richet, Charles Robert Barany, Robert Bordet, Jules Krogh, Schack August Steenberger Hill, Sir Archibald Vivian; Meyerhof, Otto Fritz; Banting, Sir Frederick Grant; Macleod, John James Richard; Einthoven, Willem; Fibiger, Johannes Andreas Grib Wagner-Jauregg, Julius Nicolle, Charles Jules Henri Eijkman, Christiaan; Hopkins, Sir Frederick Gowland Landsteiner, Karl Warburg, Otto Heinrich Adrian, Lord Edgar Douglas; Sherrington, Sir Charles Scott Morgan, Thomas Hunt Minot, George Richards; Murphy, William Parry; Whipple, George Hoyt Spemann, Hans Dale, Sir Henry Hallett; Loewi, Otto Nagyrapolt, Albert Szent-Gyorgyi Von Heymans, Corneille Jean Francois Domagk, Gerhard Dam, Henrik Carl Peter; Doisy, Edward Adelbert Erlanger, Joseph; Gasser, Herbert Spencer
ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE
FRONTIERS IN BIOSCIENCE; ALPHABETICAL LISTING OF nobel PRIZE LAUREATES IN PHYSIOLOGYAND MEDICINE, Name, Year Awarded. Kossel, Albrecht, 1910. krebs, edwin G. 1992.
http://www.bioscience.org/urllists/nobelm.htm
ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY
Zsigmondy, Richard Adolf, 1925. ALPHABETICAL LISTING OF nobel PRIZE LAUREATESIN PHYSIOLOGY AND MEDICINE. Kossel, Albrecht, 1910. krebs, edwin G. 1992.
http://www.bioscience.org/urllists/nobelc.htm

Extractions: ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN CHEMISTRY Name Year Awarded Alder, Kurt Altman, Sidney Anfinsen, Christian B. Arrhenius, Svante August ... Zsigmondy, Richard Adolf ALPHABETICAL LISTING OF NOBEL PRIZE LAUREATES IN PHYSIOLOGY AND MEDICINE Name Year Awarded Adrian, Lord Edgar Douglas Arber, Werner Axelrod, Julius Baltimore, David ... Zinkernagel, Rolf M. Source: The Nobel Prize Internet Archive
Premio Nobel De Medicina - Wikipedia
Translate this page Ver enlace http//www.nobel.se/medicine/laureates/index.html. 1993 Richard J. Roberts,Phillip A. Sharp 1992 Edmond H. Fischer, edwin G. krebs 1991 Erwin
http://es.wikipedia.org/wiki/Premio_Nobel/Medicina

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Hi-res Box Window
nobel Prizes. These include the original prize to Earl W. Sutherland Jr for hispioneering initial discoveries, as well as more recent ones to edwin G. krebs
http://www.nature.com/nrm/journal/v3/n9/slideshow/nrm911_bx1.html
The Lasker Foundation | Lasker Awards And The Nobel
Year of. Basic Award Winner, Lasker, nobel. George Wells Beadle, 1950, 1958. GeorgesJF Kohler, 1984, 1984. edwin G. krebs, 1989, 1992. Hans A. krebs, 1953, 1953.
http://www.laskerfoundation.org/awards/n_vs_l.html

Extractions: The Lasker Medical Science Awards in basic research, clinical research, special achievement and public service, which have been bestowed since l945, provide a chronicle of the progress of biomedical research over the last half-century. The Lasker Foundation is proud that many of the amazing discoveries and achievements of Lasker Award winners are recognized, in addition, by the prestigious Nobel Prize. As of 2002, sixty-six Lasker winners have gone on to win the Nobel.

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