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Schizencephaly:     more detail

The Official Parent's Sourcebook on Schizencephaly: A Revised and Updated Directory for the Internet Age by ICON Health Publications, 2004-02-13 Schizencephaly: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Peter, MD Lin, 2005 The Official Parent's Sourcebook On Schizencephaly by Icon Health Publications, 2004

lists with details

21. Ae
    Open Lipped schizencephaly. Differential Diagnosis schizencephaly versusporencephaly. Lining by gray matter distinguishes between the two.  
    http://www.med.uc.edu/neurorad/webpage/eqa.html

22. KinderStart - Health/Medical/Dental : Major Diseases/Conditions : Schizencephaly
    Support KinderStart Click on and Buy from Our Sponsors! Home Health/Medical/Dental Major Diseases/Conditions schizencephaly. Web Pages.  
    http://www.kinderstart.com/healthmedicaldental/majordiseasesconditions/schizence

23. Schizencephaly - Condition, Disease, Or Disorder Article
    schizencephaly Article relating to particular medical disease, condition,or disorder. schizencephaly. What is schizencephaly? schizencephaly  
    http://www.stopgettingsick.com/Conditions/condition_template.cfm/2489/283/1
    
    Extractions: Schizencephaly What is Schizencephaly? Schizencephaly is an extremely rare developmental disorder characterized by abnormal slits, or clefts, in the brain's cerebral hemispheres. Schizencephaly is a form of porencephaly in which there is a cyst or cavity in the cerebral hemispheres. Individuals with clefts in both hemispheres (bilateral clefts) are commonly developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in only one hemisphere) are often paralyzed on one side of the body and may have normal intelligence. Patients with schizencephaly may also have varying degrees of microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis), and reduced muscle tone (hypotonicity). Most patients have seizures. Some may have hydrocephalus. Is there any treatment?

24. Closed Lip Schizencephaly
    Subject Closed Lip schizencephaly Topic Area Neurology General Forum TheNeurology and Neurosurgery Forum Question Posted By Dawn on Monday, June 26  
    http://www.medhelp.org/forums/neuro/messages/30653a.html
    
    Extractions: When my daughter was a 8 months old we noticed that she was having some delays in her motor skills. We took her to the neurologist and her diagnosis was 1. cortical dysplasia involving the right per-sylvian region with broad gyri which are diminished in number associated with thickened cortex. There is deep enfolding of the cortex with a deep sulcus which nearly reaches the lateral ventricle. While this is reminiscent of closed lip schizencephaly, a thin band of white matter separates the enfolded gray matter from the ventricular body. 2. Absence of the septum pellucidum. 3. The optic chiasm and nerves appear to be within normal limits for size.

25. Schizencephaly
    by only one click … For Medical Professionals only. schizencephaly,,Print this article, a greymatter-lined cleft that extends through  
    http://www.amershamhealth.com/medcyclopaedia/Volume VI 1/SCHIZENCEPHALY.asp
    
    Extractions: *For Medical Professionals only, registration required Schizencephaly, a grey-matter-lined cleft that extends through the entire cerebral hemisphere from the ependymal surface of the lateral ventricle to the cerebral cortex. Two types of schizencephaly are recognized: a "closed-lip" schizencephaly in which the cleft walls are contiguous and an"open-lip" schizencephaly in which the walls are separated by wide subarachnoid spaces. The grey matter lining the cleft is usually polymicrogyric (see polymicrogyria ). The clefts can be unilateral or bilateral, symmetrical or asymmetrical and can appear anywhere in the brain. These lesions are believed to be due to in utero vascular injuries and their preferential location in the perisylvian areas follows the frontoparietal distribution of the middle cerebral artery.

26. Schizencephaly
    schizencephaly,, Print this article, Also, see schizencephaly NW TheEncyclopaedia of Medical Imaging Volume VII, schizencephaly, Fig.  
    http://www.amershamhealth.com/medcyclopaedia/Volume VII/SCHIZENCEPHALY.asp
    
    Extractions: *For Medical Professionals only, registration required Schizencephaly, neuronal migration abnormality which occurs early in gestational life, possibly around the 7th to 8th week. It may be related to a vascular event. The resulting abnormality is a seam of grey matter extending from the pial surface of the brain down towards the ependyma of the lateral ventricle. This results in a grey matter lined cleft which can be described as open lipped, where there is a cerebrospinal fluid (CSF) track between the two sides, or closed lipped, where no CSF is identified. There is usually an associated abnormal contour of the lateral ventricle where the cleft meets the ventricular surface. In a large proportion of patients (70-80%) there will also be an absence of the septum pellucidum ( Fig.1

27. Schizencephaly Associated With Bipolar Affective Disorder - S. Chaturvedi, B. Sh
    schizencephaly Associated with Bipolar Affective Disorder P. Relan, SK Chaturvedi,B. Shetty Departments of Psychiatry, National Institute of Mental Health and  
    http://www.neurologyindia.com/vol50-2/1588ab.php
    
    Extractions: Summary : Schizencephaly is a rare congenital anomaly of the brain, characterized by formation of abnormal unilateral or bilateral clefts in the cerebral hemispheres. It often manifests with partial seizures, mental retardation and hemiparesis. Only two cases of schizencephaly associated with psychosis have been reported in the literature. A patient of schizencephaly, who had bipolar affective disorder is described. It has been compared with the earlier two reported cases of schizencephaly associated with pyschosis. Full Article Editor : S.Prabhakar

28. 1Up Health > Health Links Directory > Conditions And Diseases: Genetic Disorders
    127). Sites. NINDS schizencephaly Information sheet compiled the NationalInstitute of Neurological Disorders and Stroke. Pediatric  
    http://www.1uphealth.com/links/genetic-disorders-schizencephaly.html
    
    Extractions: The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only they do not constitute endorsements of those other sites.

29. 1Up Health > Schizencephaly - Birth Defects & Genetic Disorders
    schizencephaly . Read detailed information about schizencephaly . Includesa set of questions and answers related to schizencephaly  
    http://www.1uphealth.com/medical/disease/birth-defects-genetic-disease/schizence
    
    Extractions: The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only they do not constitute endorsements of those other sites. Home Contact Us Privacy Links Directory

30. Schizencephaly
    schizencephaly. schizencephaly is an extremely rare developmental disorder characterizedby abnormal slits, or clefts, in the brain’s cerebral hemispheres.  
    http://oci.mcw.edu/article/921961352.html
    
    Extractions: Subscribe now >> Schizencephaly is an extremely rare developmental disorder characterized by abnormal slits, or clefts, in the brain’s cerebral hemispheres. Schizencephaly is a form of porencephaly in which there is a cyst or cavity in the cerebral hemispheres. Individuals with clefts in both hemispheres (bilateral clefts) are commonly developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in only one hemisphere) are often paralyzed on one side of the body and may have normal intelligence. Patients with schizencephaly may also have varying degrees of microcephaly (abnormally small head), mental retardation, hemiparesis or quadriparesis (partial or complete paralysis), and reduced muscle tone (hypotonicity). Most patients have seizures. Some may have hydrocephalus. Treatment for individuals with schizencephaly generally consists of physical therapy, treatment for seizures, and, in cases that are complicated by hydrocephalus, a shunt (a surgically implanted tube that diverts fluid from one pathway to another).

31. Virtual Hospital: Radiology Resident Case Of The Week: Schizencephaly
    Radiology Resident Case of the Week. schizencephaly. April 26, 1996. 1993. pg. 204.ACR Code 132.1423. Keywords 1. schizencephaly 2. clefts 3. brain malformations.  
    http://www.janela1.com/vh/docs/v0000962.htm
    
    Extractions: The cleft may be narrow or closed (type 1) or wide and open (type 2). It is frequently associated with complete or partial absence of the cavum septum pellucidum in approximately 80-90% of cases. the cleft is usually located near the pre- or postcentral gyri. The clefts can be unilateral or bilateral. Polymicrogyria, microcephaly, and gray matter heterotopia have also been noted. Optic nerve hypoplasia has been noted in 33% of cases, with possibility of blindness. Prognosis is poor, with severe intellectual impairment, spastic tetraplegia and blindness. Miscellaneous

32. Schizencephaly Resources
    schizencephaly. schizencephaly Support Group. Back toHomepage Back to Index Back to Assistance .  
    http://www.specialink.com/e-curbcuts/MainCategories/Assistance/Schizen.htm

33. Schizencephaly And Porencephaly :
    schizencephaly and porencephaly porencephaly.  
    http://www.angelfire.com/nc/neurosurgery/GGSchizenc.htm

34. Schizencephaly And Porencephaly :
    schizencephaly and porencephaly schizencephaly. main page. more  
    http://www.angelfire.com/nc/neurosurgery/GGSchizenc2.htm

35. Schizencephaly
    schizencephaly schizencephaly factsheet National Institutefor Neurological Disorders and Stroke. disclaimer.  
    http://www.ion.ucl.ac.uk/library/patient/schizen.htm

36. Schizencephaly : Meddie Health Search
    ITEMS LINKS NINDS schizencephaly Information sheet compiled theNational Institute of Neurological Disorders and Stroke. (Rating  
    http://www.meddie.com/search/Health/Conditions_and_Diseases/Genetic_Disorders/Sc

37. Schizencephaly
    No messages are screened for content. schizencephaly. She is now almost2. and i still dont know a whole lot about schizencephaly.  
    http://neuro-www.mgh.harvard.edu/forum_2/GeneralNeurologyF/10.30.993.23PMschizen
    
    Extractions: This Web Forum is not moderated in any sense. Anyone on the Internet can post articles or reply to previously posted articles, and they may do so anonymously. Therefore, the opinions and statements made in all articles and replies do not represent the official opinions of MGH and MGH Neurology. Neither is MGH or MGH Neurology responsible for the content of any articles or replies. No messages are screened for content. This article submitted by Kimberly on 10/30/99. Hi, My name is Kimberly, i have a daughter that was diagnosed with bilateral open lip schizencephaly when she was 6 months old. She is now almost 2. and i still dont know a whole lot about schizencephaly. there is not a lot of info online on this subject. if anyone has any info they can pass along.that would be much appreciated. thank you very much Kimberly Next Article

38. Schizencephaly
    schizencephaly. This article submitted by Hollis McEvilly on 9/18/95. I am lookingfor information on schizencephaly . It is a very rare disorder.  
    http://neuro-www.mgh.harvard.edu/neurowebforum/ChildNeurologyArticles/Schizencep
    
    Extractions: I am looking for information on "Schizencephaly". It is a very rare disorder. We have been given very limited answers to our questions, because they are not sure of long term outcomes. My granddaugher is now 2 years old, she is having speed, physical and occupational therapy once a week. She is coming along very well she is about 3 months behind in development so far. Her speech is not very good as yet, hopefully that will get better with therapy. Any information would be very helpful to us. Thanking you in advance. Next Article

39. MIR Teaching File Case Pb011
    Rating D., Q. Diagnosis schizencephaly. Brief history Full history/Diagnosisis available below. Diagnosis schizencephaly. Full history  
    http://gamma.wustl.edu/pb011te111.html
    
    Extractions: Case Author(s): Yungao Ding, MD, PhD and Henry Royal, MD , 5/14/2001 . Rating: #D., #Q. Man with refractory complex partial seizure Images: Coronal brain emission image View main image(pb) in a separate image viewer View second image(pb). Transaxial brain emission image View third image(mr). Coronal MRI of the brain View fourth image(mr). Transaxial MRI of the brain Full history/Diagnosis is available below 26 year old man with left frontoparietal open-lip schizencephaly with overlying polymicrogyria presents with refractory complex partial seizures. Clinical evaluation suggests seizures most likely arising from the left frontal region. 9.0 mCi F-18 FDG, i.v. A defect in the left frontoparietal cortex is noted corresponding to the open-lip schizencephaly on MRI. The left hemisphere is smaller than that of the right and there is enlargement of the left lateral ventricle as showed on MRI. Schizencephaly, open- or close-lip, is associated with polymicrogyria/agyria in the adjacent cortex. Patients present with seizure, developmental delay, mental retardation and possible blindness if associated with optic nerve hypoplasia.

40. ORPHANET® : Schizencephaly
    Translate this page ORPHANET. ORPHANET database access. schizencephaly.Direct access to details Alias Home Page.  
    http://www.orpha.net/static/GB/schizencephaly.html

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