41. Disease Category Listing (328): Anal Fissures Clinical Trials anal fissures. There are no studies currently listed in this categoryon the CenterWatch web site. Back to Clinical Trials by Medical Areas. http://www.centerwatch.com/studies/cat328.htm

Clinical Trials: Anal Fissures There are no studies currently listed in this category on the CenterWatch web site. Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials. Trial listing updated: March 28, 2003 at 3:29:02 PM Patient Resources: [ Trial Listing Notification Services Drug Directories About Clinical Research ... Patient Bookstore Professional Resources: [ Research Center Profiles Industry Provider Profiles Industry News Professional Resources ... Professional Bookstore General: [ Search Site Map Your Privacy CW World ... Home This site was developed in association with Illumina Interactive of Boston, MA

42. Therapeutic Areas Home » Current Projects » anal fissures. Printer Friendly Version. Untilrecently, most chronic anal fissures were treated with surgery. http://www.slapharma.com/pages/projects-anal-fissures.html

Home Therapeutic Areas Anal fissures Printer Friendly Version What is an anal fissure? An anal fissure is a small split in the skin of the anus (back passage). This may be caused by passage of a hard stool and is associated with raised internal anal sphincter pressure (muscle spasm of the back passage). What symptoms does an anal fissure cause? An anal fissure causes pain on opening the bowels and there is often some blood on the toilet paper after wiping. Some people also notice itching around the anus. Anal fissure is often confused with piles (haemorrhoids), which are usually not painful. Is an anal fissure dangerous? An anal fissure is painful and irritating but is not dangerous. As some other conditions cause pain and bleeding from the bottom, it is important that you visit your doctor for an examination to confirm the diagnosis. What tests are needed?

43. SLA Scientific Articles DILTIAZEM for anal fissures. ·, Topical 2% diltiazem in the treatment of chronicanal fissures. , Diltiazem is effective treatment for chronic anal fissures. http://www.slapharma.com/pages/articles-new.html

Home Scientific Articles DILTIAZEM PHENYLEPHRINE NICOTINE EPA ... BETHANECHOL DILTIAZEM for Anal Fissures Topical 2% diltiazem in the treatment of chronic anal fissures. Abstract Diltiazem lowers resting anal sphincter pressure - a potential low side effect alternative to glyceryl trinitrate for fissures. Abstract Topical diltiazem and bethanechol decrease anal sphincter pressure without side effects. Abstract Randomised controlled trial shows that glyceryl trinitrate heals anal fissures, higher doses are not more effective, and there is a high recurrence rate. Abstract Diltiazem is effective treatment for chronic anal fissures.

44. VioWorks -- Diltiazem Heals GTN-Resistant Chronic Anal Fissures If you are not already registered, please register for free beforelaunching. Diltiazem Heals GTNResistant Chronic anal fissures. http://www.vioworks.com/Player/key.asp?p=553

45. Dr. Christophers Complete Tissue Ointment - (BF&C), Used For Anal Fissures An Complete Tissue Ointment (BF C Ointment). Bone, flesh and cartilage ointmentOak Bark, Marshmallow Root, Mullein Herb, Wormwood, Lobelia http://www.herbsfirst.com/discriptions/bf&coint.html

Complete Tissue Ointment Bone, flesh and cartilage ointment: Oak Bark, Marshmallow Root, Mullein Herb, Wormwood, Lobelia, Skullcap, Comfrey Root, Walnut Bark (or leaves) and Gravel Root in an olive oil and beeswax base. capsules bulk syrup ointment, oil Testimonials Spinal Disorders and Backaches: Although we always want to work on the cause of backache, we can relieve the symptoms by using the cayenne heating balm . This consists of cayenne pepper, wintergreen oil, pure mint crystals, and other essential oils in a base of olive oil and untreated beeswax-apply sparingly to sore places. We have found that the works well together with the cayenne ointment. One takes the other into the skin more quickly and brings relief. [NL 3-12] Burns: Wonderful for healing burns - aids in healing and in pain. For more information go to: and Question : What can be done to clear up stretch marks on the body? Answer: Used by permission, taken from The Complete Writings of Dr. John R. Christopher, CD ROM The FDA is having all the herb companies put a warning label on any product that has comfrey in it. The label says the following: Warning: External use only. Consuming this product can cause serious liver damage. This product contains Comfrey. Comfrey contains pyrrolizidine alkaloids, which may cause serious illness or death. This product should not be taken orally, used as a suppository, or applied to broken skin. For futher information contact the FDA at http://www.cfsan.fda.gov

46. BF & C Ointment For Use In Anal Fissures, Skin Disorders, Etc. BF C Ointment. Bone, flesh and cartilage ointment Oak Bark, MarshmallowRoot, Mullein Herb, Wormwood, Lobelia, Skullcap, Comfrey http://www.herbsfirst.com/discriptions/bf&cointDM.html

Bone, flesh and cartilage ointment: Oak Bark, Marshmallow Root, Mullein Herb, Wormwood, Lobelia, Skullcap, Comfrey Root, Walnut Bark (or leaves) and Gravel Root in an olive oil and beeswax base. capsules bulk syrup ointment, oil Testimonials Spinal Disorders and Backaches: Although we always want to work on the cause of backache, we can relieve the symptoms by using the cayenne heating balm . This consists of cayenne pepper, wintergreen oil, pure mint crystals, and other essential oils in a base of olive oil and untreated beeswax-apply sparingly to sore places. We have found that the works well together with the cayenne ointment. One takes the other into the skin more quickly and brings relief. [NL 3-12] Burns: Wonderful for healing burns - aids in healing and in pain. For more information go to: and Question : What can be done to clear up stretch marks on the body? Answer: Used by permission, taken from The Complete Writings of Dr. John R. Christopher, CD ROM The FDA is having all the herb companies put a warning label on any product that has comfrey in it. The label says the following: Warning: External use only. Consuming this product can cause serious liver damage. This product contains Comfrey. Comfrey contains pyrrolizidine alkaloids, which may cause serious illness or death. This product should not be taken orally, used as a suppository, or applied to broken skin. For futher information contact the FDA at http://www.cfsan.fda.gov

47. The Medical Procedures Center, P.C. - Anal Fissures And Pruritus Ani ("itchy But anal fissures and Pruritus Ani ( itchy butt ). Many patients presentto our office with symptoms of severe itching around the anus. http://www.mpcenter.net/patient_ed/anal_fissures_pruritis.html

The Medical Procedures Center, P.C. "We treat people, not just problems." John L. Pfenninger, M.D. 4909 Hedgewood Drive, Midland, MI 48640 Visit our Website at http://www.MPCenter.net Anal Fissures and Pruritus Ani ("itchy butt") Many patients present to our office with symptoms of severe itching around the anus. Others come thinking they have hemorrhoids because they have experienced bright red rectal bleeding. On physical exam, physicians often find an area that is very sore and irritated with very fine cracks in the skin. These cracks are called fissures. Some fissures are more external on the skin and readily visible. Other fissures are situated more deeply inside. Your physician will be able to determine at the exam which type of fissure you’ve had and what the appropriate treatment is. If yours are the ones that are more visible, then this handout is appropriate for you. Many people feel that their itching is due to being "dirty down there". Many times, it is over-cleansing that causes the problem. After having a bowel movement, either wash with a washcloth and warm water or use Tucks Medicated Wipes. A less expensive method is to use baby wipes that do not contain alcohol. Scrubbing is not necessary. Just gentle cleansing. It is important to use hypoallergenic soaps and shampoos. Many people with this condition have fair skin. They are very sensitive to perfumes and dyes. I like to recommend Aveeno, Oilatum, or Lever 2000 soaps. Anything that states that it’s hypoallergenic would probably suffice. For those who really have problems, they will also need to get a hypoallergenic shampoo. We use Envi.

48. DG DISPATCH - ASCRS Nitroglycerin Ointment Effective For DG DISPATCH ASCRS Nitroglycerin Ointment Effective For TreatingChronic anal fissures By Margaret Pearson Special to DG News. http://www.pslgroup.com/dg/1d809e.htm

49. Adult Health Advisor 2002.1: Anal Fissure anal fissures are a common disorder, particularly in persons with irregularor hard bowel movements. What can be done to help prevent anal fissures? http://www.med.umich.edu/1libr/aha/aha_analfiss_crs.htm

Adult Health Topics All Health Topics Find a UMHS Doctor Search Adult Topics Search All Topics T his information is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. McKesson Clinical Reference Systems: Adult Health Advisor 2002.1 Anal Fissure What is an anal fissure? An anal fissure is a small tear or break in the skin at the outer tip of the anal canal. The anus is the opening through which bowel movements pass. Anal fissures are a common disorder, particularly in persons with irregular or hard bowel movements. How does it occur? Tears in the anal skin occur during bowel movements when hard, dry stools are passed. They may also be associated with: straining at bowel movements when you are constipated stress or tension waiting too long to have a bowel movement (BM) constipation after surgery What are the symptoms?

50. Gihealth.com - Built For Patient Satisfaction anal fissures Email this Article to a Friend Just like a papercut If you have everhad a painful papercut on your finger, you understand all about anal fissures http://www.gihealth.com/html/education/analFissure.html

Patient Education Patient Pamphlets Anal Fissures Just like a papercut If you have ever had a painful papercut on your finger, you understand all about anal fissures. The anus is the ring-like sphincter or valve at the end of your rectum. It opens and closes on your command to allow a bowel movement when convenient. An anal fissure is a small tear in the rim of the anus - just like a tiny papercut. One problem with a papercut is that every time you use your hands, you tend to break open the small wound which delays healing causes more pain. The same holds true with an anal fissure. Every time you have a bowel movement, the anus is stretched and the fissure can possibly be reopened causing more symptoms. This makes some anal fissures chronic and difficult to heal. This problem is quite common and may cause considerable misery. What causes an anal fissure? The anal opening is only so big. To have a bowel movement the anal sphincter relaxes and open up as much as it can, but the stool must be still be soft enough to squeeze through the opening. If the stool is dry and hard, the anal sphincter is forced to open even wider than normal. This difficult passage can cause a tear in the rim of the anal opening, resulting in a fissure. Other causes of a fissure include severe diarrhea, inflammatory bowel disease, and sexually related trauma. Classification of fissures Fissures are graded as superficial or deep. A superficial fissure does not extend full thickness through the skin; a deep fissure results in exposing underlying muscle fiber. Fissures are also graded as acute or chronic. An acute fissure is less than thirty days duration; a chronic fissure is present for greater than thirty days.

51. Anal Fissure anal fissures are usually related to abnormal bowel movements. There are alsoseveral medical conditions that can cause anal fissures, including http://atoz.iqhealth.com/HealthAnswers/encyclopedia/HTMLfiles/182.html

anal fissure Images (Click to view larger image) Alternative Names anal ulcer Definition An anal fissure is a tear in the internal lining of the anus. This area is called the anal mucosa. This break in the anal lining often reopens during bowel movements. The result is bright red blood and intense pain. What is going on in the body? An anal fissure is a tear in the bowel lining. It causes painful, bloody bowel movements. It is often confused with hemorrhoids, which are painful swellings at the anus caused by enlarged veins. A fissure can be acute or chronic. The chronic condition is often associated with a buildup of tissue at the external end of the tear. This is called a sentinel pile and may be noticed by an affected person. The internal end may also have a buildup of tissue that an affected person can rarely see. When a fissure is present, the mucosa of the anus opens each time it is stretched to allow for a bowel movement. This continual opening prevents healing. It can also leave scar tissue. Most chronic fissures are in the center of the back of the anus. The anal sphincter muscles need to relax for a person to have a bowel movement. A person with a fissure may have muscles that are too tight. This makes bowel movements painful.

52. Colon And Rectal Surgeons Of Long Island, P.C. - Anal Fissure are offering special medicated creams such as nitroglycerin and nifedipine whichhave been shown to decrease the time to healing of anal fissures when applied http://www.colonandrectalsurgeons.com/AnalFissure.html

Main Page Our Offices Bethpage East Setauket Riverhead Our Doctors Arnold R. Leiboff, M.D. Maria A. Basile, M.D. Office Policies Health Plans ... Riverhead Updated 7 January 2002. Prepared by Colon and Rectal Surgeons of LI, P.C. with the assistance of Bernstein + Sons, Information Systems Consultants

53. Hemorrhoids - Proven Natural Treatment. (hemorroids, Hemmoroids, Hemroids) Hemorrhoids products, as well as our specially formulated products for pregnancy,will eliminate your hemorrhoids, bleeding or anal fissures quickly and http://www.amoils.com/hemorrhoids.html

Hemorrhoids Page Product Selection Home Heal Herpes Heal Warts Heal Eczema ... - Order Now - Links About Us Testimonials Medical Studies Affiliate Program ... Health Links Reference Address Information Healing Natural Oils 12810 Corbett Court San Diego, CA 92130 Toll Free 866 445 5433 Contact us by email - Order Now - Medical Studies return to the top ... return to the top Natural Treatment for Hemorrhoids and Bleeding Hemorrhoids Our Heal Hemorrhoids and Heal Bleeding Hemorrhoids products, as well as our specially formulated products for pregnancy, will eliminate your hemorrhoids, bleeding or anal fissures quickly and effectively. These products provide instant relief from pain and reduce swelling rapidly with no skin irritation. Results are guaranteed or you will receive a full refund. (see testimonials below)

54. Anal Fissure Rarely anal fissures can be associated with more serious inflammatory bowel conditions.Probably about half of fissures will heal with little difficulty. http://www.studenthealth.co.uk/leaflets/AnalFissure.htm

Anal Fissure www.StudentHealth.co.uk This is a very common condition, and is a small tear in the lining of the anal canal, which can cause pain, bleeding and itching. It is commonly caused by constipation, but often occurs after a bout of diarrhoea or for no obvious reason. Rarely anal fissures can be associated with more serious inflammatory bowel conditions. Probably about half of fissures will heal with little difficulty. Taking Ispaghula husk, which is a bulk forming laxative may aid the healing process, particularly if your diet is low in fibre. An anaesthetic cream is sometimes prescribed if there is a lot of pain, but sensitivity to these preparations may occur. Chronic fissures (a fissure that has not healed in about 6 weeks) may require a more active intervention. Traditionally this involves surgery usually with some form of stretching of the anal sphincter. More recently, Glyceryl trinitrate spray (GTN) has been used with reasonable success.

55. Anal Fissures : Meddie Health Search search options. Home Health Conditions and Diseases DigestiveDisorders Anorectal anal fissures. ITEMS LINKS Anal Fissure http://www.meddie.com/search/Health/Conditions_and_Diseases/Digestive_Disorders/

HOME ADD A LINK MODIFY A LINK NEW LINKS ... TOP RATED Search Meddie: the entire directory only this category More search options Home Health Conditions and Diseases ... Anorectal : Anal Fissures ITEMS: LINKS: Anal Fissure: Patient Brochure An explanation of what this is, the causes, treatment and surgery. (Rating: 0.00 Votes: 0) Rate It Anal Fissures Self Help page for those with anal fissures. (Rating: 0.00 Votes: 0) Rate It HOME ADD A LINK MODIFY A LINK ... Design © ISC Enterprises Inc.

56. Bianca Navigation Bar Return To Top Level Posts Date Sat Feb 16 203935 2002 From Arnold Subject anal fissures I havebleeding fissures up and on the outside of my barking spider . http://www.bianca.com/interests/drugs/bbs/posts/2002_Feb_16/557/557.html

Return To: Top Level Posts Date: Sat Feb 16 20:39:35 2002 From: Arnold Subject: Anal fissures I have bleeding"fissures" up and on the outside of my"barking spider". My boyfriend will not stop using the "tradesman's entrance". I am obviously a"crafty butcher".Has anybody got any suggestions about this,or will it just go away like my"sausage jockey"of a boyfriend says? View Top Level Message Thread: Anal fissures by Arnold on Sat Feb 16 20:39:35 2002 Re: Anal fissures by bug on Sun Mar 10 21:12:30 2002 Re: Anal fissures by Lothar on Sun Mar 10 20:56:29 2002 Re: Re: Anal fissures by anonymous on Sun Mar 10 21:17:35 2002 all material submitted to this site is the sole responsibility of the submitter. bianca@bianca.com

57. Bianca Navigation Bar Return To Top Level Posts In Response To anal fissures Date Sun Mar 10 211230 2002 Frombug Subject Re anal fissures I had a perirectal absess that http://www.bianca.com/interests/drugs/bbs/posts/2002_Feb_16/557/559.html

Return To: Top Level Posts In Response To: Anal fissures Date: Sun Mar 10 21:12:30 2002 From: bug Subject: Re: Anal fissures I had a perirectal absess that caused me to have four anal fistulectomies. In other words.....I had four surgeries very, very close to my "barking spider". From someone who had to endure alot of PAIN to heal the fistula, my advice would be to stop allowing your boyfriend to use the "tradesman's entrance". His desire, or need, to please himself this way can lead to alot of medical pain for you if the anal fissures worsten, and there is no way that they will get any better if this continues. My boyfriend also liked the "trademan's entrance" before my operations and I'm still not sure that this was the cause of a fistula, or absess, to form. The inside lining of your rectum can easily become infected by several causes. I'm not a doctor, so in lament terms, this is the only way I can express it. View Top Level Message Thread: Anal fissures by Arnold on Sat Feb 16 20:39:35 2002 Re: Anal fissures by bug on Sun Mar 10 21:12:30 2002 Re: Anal fissures by Lothar on Sun Mar 10 20:56:29 2002 Re: Re: Anal fissures by anonymous on Sun Mar 10 21:17:35 2002 all material submitted to this site is the sole responsibility of the submitter.

58. Dermatology.cdlib.org/rxderm-archives/anal-fissures anal fissures From Haines Ely szdrskin@peseta.ucdavis.edu One of the neatestletters to the editor I have seen in a long time was written in the NEJM by http://dermatology.cdlib.org/rxderm-archives/anal-fissures

ANAL FISSURES From: Haines Ely One of the neatest letters to the editor I have seen in a long time was written in the NEJM by Stephen R. Gorfine M.D.titled Topical Nitroglycerine Therapy for Anal Fissures and Ulcers, NEJM 333(17) 1156-7, 1995. Anal sphincter hypertonicity is associated with painful anal fissures and ulcers. A derangement of nitric oxide regulation may cause this spasticity. Nitroglycerine was applied as 200mg in an ointment and the investigators asked the fourty patients treated to rate their pain on a scale of one to ten. The mean pain scores before and after treatment were 4.8 and 1.4. The patients were instructed to apply the ointment QID. Fissures healed in two weeks in 30% of the patients, in four weeks or less in 70% of patients. Side effects were limitted to mild transient headaches.

59. AYC: Anal Fissure Or Anal Ulcer Analrectal disorders include anal itch, hemorrhoids (both internal and external),anal fissures (both acute and chronic), anal abscesses, and fistula-in-ano. http://alwaysyourchoice.com/ayc/sex/gay/anal_fissure.php

Sexual Health Issues Gay and Lesbian Anilingus Anal Intercourse ... Information Anal Fissure or Anal Ulcer Basic Information Ano-rectal disorders are common occurrences for at least 50% of the U.S. population. They affect children and adults, males and females, gay and straights alike. There seem to be several causes for these fissures. Besides a traumatic bowel movement trauma from anal penetration is often common in gay men. The trauma does not necessarily have to be caused by a penis but by any blunt invasion of the anal cavity opening which can include sex toys. If caused by sexual penetration the fissures may occur almost anywhere unlike the fissures caused by traumatic bowel movement which are most often found in the posterior midline section. Infants or young children seem also to be at risk for anal fissures, sometimes in an acute form.

60. ANAL FISSURES anal fissures Tears or superficial lacerations that can occur in themucosa that lines the anal canal. ©1998-2002 DSHI Systems, Inc http://www.mymedadvice.com/html/0/gls_0302.htm

ANAL FISSURES - Tears or superficial lacerations that can occur in the mucosa that lines the anal canal.

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