61. Ask Dr Stoll - 1997 Aplastic Anemia Post Archive aplastic anemia. Posts to Ask Dr Stoll BB regarding aplastic anemia. When I firstentered practice, nearly 40 years ago, aplastic anemia was almost unknown. http://askwaltstollmd.com/archives/anemia.html

Dr Stoll Home Dr Stoll BB Aplastic Anemia Posts to Ask Dr Stoll BB regarding Aplastic Anemia There have been many posts to the Ask Dr Stoll Bulletin Board (BB) regarding Aplastic Anemia and other blood disorders. Several of them have been archived here. The archive is roughly chronological. I hope you find it useful. Summary for aplastic anemia: This type of anemia is, perhaps, the most severe one can have since it is caused by a shutdown of the person's ability to MAKE blood cells. That means that, even if all the nutrients are present, the factory cannot make them into cells. The only known, conventional, solution is repeated blood transfusions and eventually even that will not help and the person dies. There are medications that will help for a while but it is really whipping a deadly tired horse. Eventually, they will not work because the horse is dead. It is now known that the most common cause of this condition is MCS (Multiple Chemical Sensitivities) and how early in life this happens is genetically determined. When I first entered practice, nearly 40 years ago, aplastic anemia was almost unknown. In 30+ years of practice I never saw a case. However, now it is almost an epidemic. This is NOT a case of sudden evolution of mankind but a result of the tremendous increase of invented chemicals we are all exposed to every day.

62. Aplastic Anemia -Contact A Benzene Lawyer- Aplastic Anemia! aplastic anemia. aplastic anemia has been directly linked to exposureto toxins such as benzene. Workers are at the highest risk http://www.acute-myelogenous-leukemia.com/aplastic_anemia.html

Benzene History Benzene FAQ Benzene Health Benzene Risk ... Site Map Aplastic Anemia Aplastic anemia has been directly linked to exposure to toxins such as benzene. Workers are at the highest risk for benzene related illnesses like aplastic anemia. By reducing the amount of exposure to benzene that occurs, workers can avoid serious instances of illness. Learning to recognize signs and symptoms of various occupational risks can help prevent illnesses and conditions such as aplastic anemia to progress into a more serious problem. Symptoms of aplastic anemia can sometimes be mistaken for other more common problems. If an individual has been exposed to benzene and is feeling symptoms of fatigue, rapid heart rate, shortness of breath, easy bruising, rash, prolonged bleeding, or has frequent infections this may be an indicator that aplastic anemia is present. Allowing aplastic anemia to progress without being treated can lead to death. If you would like more information on aplastic anemia due to benzene exposure, please

63. Aplastic Anemia .......MAIN SEARCH INDEX aplastic anemia. aplastic anemia is a disorder in which the bonemarrow greatly decreases or stops production of blood cells. http://www.hendrickhealth.org/healthy/000138.htm

MAIN SEARCH INDEX Aplastic anemia Definition Description Causes and symptoms Diagnosis ... Resources Definition Aplastic anemia is a disorder in which the bone marrow greatly decreases or stops production of blood cells. Description The bone marrow (soft tissue which is located within the hard outer shell of the bones) is responsible for the production of all the types of blood cells. The mature forms of these cells include red blood cells, which carry oxygen throughout the body; white blood cells, which fight infection; and platelets, which are involved in clotting. In aplastic anemia, the basic structure of the marrow becomes abnormal, and those cells responsible for generating blood cells (hematopoietic cells) are greatly decreased in number or absent. These hematopoietic cells are replaced by large quantities of fat. Yearly, aplastic anemia strikes about 5-10 people in every one million. Although aplastic anemia strikes both males and females of all ages, there are two age groups that have an increased risk. Both young adults (between 15-30 years of age) and the elderly (over the age of 60) have higher rates of aplastic anemia than the general population. While the disorder occurs worldwide, young adults in Asia have a higher disease rate than do populations in North America and Europe. Causes and symptoms Aplastic anemia falls into three basic categories, based on the origin of its cause: idiopathic, acquired, and hereditary.

64. Aplastic Anemia And Viral Hepatitis aplastic anemia and viral hepatitis Prof. Earlier reports implicatedhepatitis NonA,NonB in hepatitis induced aplastic anemia (4;20). http://www.ikp.unibe.ch/lab2/aplan.html

Aplastic anemia and viral hepatitis Prof. J. Reichen In ten patients referred to the NIH for supposed viral hepatitis induced aplastic anemia, serologic tests against hepatitis A, B and C were negative; 3 had hepatitis G; the authors conclude that it is immune-mediated and probably not related to the known hepatitis viruses (1). In a prospective study of 5500 children with viral hepatitis aplastic anemia was observed in 4 (0.07 %); none had hepatitis A or B (19). Hepatitis A. Case reports, mostly in children (7). A prospective case control study from Thailand found the presence of IgG but not IgM to confer a relative risk of 2.9 for the development of aplastic anemia; they conclude that hepatitis A is a surrogate marker for an unknown enteric pathogen (10). In the prospective Swedish study, hepatitis A was never implicated (19). Hepatitis B: Up to 1988 four case reports (14). However, in the prospective Swedish study hepatitis B was never implicated (19). Hepatitis C: Most likely not associated. Although there is a high prevalence of anti-HCV (17/90) in patients with aplastic anemia this increases with duration and number of transfusions and is therefore probably transfusion related (16). In one case, autoimmune phenomena associated with hepatitis C (anti-LKM positive) was implicated (18). Hepatitis G : Case reports have implicated hepatitis G because of the temporal association (3;6;11;12). Prevalence about 1.5 % in blood donors; same prevalence in patients with aplastic anemia (26.3 %) as in multitransfused controls (23.1 %), therefore probably not implicated (2).

65. 1Up Health > Idiopathic Aplastic Anemia > Causes, Incidence, And Risk Factors Of Comprehesive information on Idiopathic aplastic anemia (Anemia idiopathicaplastic). Idiopathic aplastic anemia Causes, Incidence, and Risk Factors. http://www.1uphealth.com/health/idiopathic_aplastic_anemia_info.html

1Up Health Idiopathic aplastic anemia Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Idiopathic aplastic anemia Information Idiopathic aplastic anemia Causes, Incidence, and Risk Factors Alternative names : Anemia - idiopathic aplastic Definition : Idiopathic aplastic anemia is a failure of the bone marrow to properly form all types of blood cells. Causes, Incidence, and Risk Factors Idiopathic aplastic anemia is a condition that results from injury to the stem cell, a cell that gives rise to other cell types after it divides. Consequently, there is a reduction in all cell types red blood cells, white blood cells and platelets with this type of anemia , which is called pancytopenia. The cause of idiopathic aplastic anemia is unknown, but is thought to be an autoimmune process (the body reacting against its own cells). Causes of other types of aplastic anemia may be chemotherapy radiation therapy toxins , drugs, pregnancy , congenital disorder, or systemic lupus erythematosus Symptoms arise as the consequence of bone marrow failure. Anemia (low red blood cell count ) leads to fatigue and weakness . Low white blood cell count, or leukopenia, causes an increased risk of infection. Low platelet count, or

66. 1Up Health > Secondary Aplastic Anemia > Causes, Incidence, And Risk Factors Of Comprehesive information on Secondary aplastic anemia (Acquired aplasticanemia, Anemia secondary aplastic). Covers info such http://www.1uphealth.com/health/secondary_aplastic_anemia_info.html

1Up Health Secondary aplastic anemia Alternative Medicine Clinical Trials ... Health Topics A-Z Search 1Up Health Secondary aplastic anemia Information Secondary aplastic anemia Causes, Incidence, and Risk Factors Alternative names : Acquired aplastic anemia, Anemia - secondary aplastic Definition : Secondary aplastic anemia is a failure of the blood-cell forming capacity of the bone marrow that affects all blood-cell types. Causes, Incidence, and Risk Factors Secondary aplastic anemia is a condition that is a result of injury to the stem cell, a cell that gives rise to other blood cell types when it divides and differentiates. Consequently, there is a reduction in all types of blood cells: red blood cells, white blood cells, and platelets (which is called pancytopenia). Causes of secondary aplastic anemia include chemotherapy , drug therapy to suppress the immune system, radiation therapy toxins such as benzene or arsenic, drugs, pregnancy , and congenital disorders. When the cause is unknown, it is then referred to as idiopathic aplastic anemia Symptoms arise as a consequence of bone-marrow failure. Anemia (a low

67. Aplastic Anemia ....... aplastic anemia. Definition. aplastic anemia is a disorder in which the bone marrowgreatly decreases or stops production of blood cells. http://www.healthatoz.com/healthatoz/Atoz/ency/aplastic_anemia.html

Encyclopedia Index A Home Encyclopedia Encyclopedia Index A Aplastic anemia Definition Aplastic anemia is a disorder in which the bone marrow greatly decreases or stops production of blood cells. Description The bone marrow (soft tissue which is located within the hard outer shell of the bones) is responsible for the production of all the types of blood cells. The mature forms of these cells include red blood cells, which carry oxygen throughout the body; white blood cells, which fight infection; and platelets, which are involved in clotting. In aplastic anemia, the basic structure of the marrow becomes abnormal, and those cells responsible for generating blood cells (hematopoietic cells) are greatly decreased in number or absent. These hematopoietic cells are replaced by large quantities of fat. Yearly, aplastic anemia strikes about 5-10 people in every one million. Although aplastic anemia strikes both males and females of all ages, there are two age groups that have an increased risk. Both young adults (between 15-30 years of age) and the elderly (over the age of 60) have higher rates of aplastic anemia than the general population. While the disorder occurs worldwide, young adults in Asia have a higher disease rate than do populations in North America and Europe. Causes and symptoms Aplastic anemia falls into three basic categories, based on the origin of its cause: idiopathic, acquired, and hereditary.

68. Aplastic Anemia And Myelodysplasia Association - Alberta aplastic anemia and Myelodysplasia Association of Canada. Alberta Chapter Backto aplastic anemia and Myelodysplasia Association of Canada. http://www.aamac.ualberta.ca/alta.html

Aplastic Anemia and Myelodysplasia Association of Canada Alberta Chapter We are currently a group of 15-20 people who meet once a year and work in our local communities to provide patient support for people with aplastic anemia, myelodysplastic syndromes and PNH, to disseminate information about the disorders, to support the Canadian Blood Services programs directly affecting patients with bone marrow failure diseases, and to raise funds to support research. For more information about the Alberta Chapter, please contact: S. Marchesin 10003 - 82 Street Edmonton, Alberta tel: (780) 465-3414 smarchesin@shaw.ca < Back Home This file last updated: document.write(document.lastModified) // unhide >

69. Educational Needs Of The Child With Aplastic Anemia - Association Of Pediatric O Educational Needs of the Child with aplastic anemia Joan M. O’Brien,BSN RN CPON. aplastic anemia is a rare but complicated illness. http://www.apon.org/i4a/pages/index.cfm?pageid=297

70. Hematopathology reduced. This is a case of aplastic anemia. Of sometimes infection. When noknown cause can be found, it is termed idiopathic aplastic anemia. http://medlib.med.utah.edu/WebPath/HEMEHTML/HEME052.html

Hematopoietic elements in this bone marrow biopsy are markedly reduced. This is a case of aplastic anemia. Of course, besides, RBC's the platelets and granulocytes will often be diminished. Sometimes a drug or toxin is the cause and sometimes infection. When no known cause can be found, it is termed idiopathic aplastic anemia.

71. ATE Responses SUBJ (01/00) CONNECTION WITH aplastic anemia. I have disorder. One of theyounger female members of my family has aplastic anemia Ed. Note http://www.mdausa.org/experts/question.cfm?id=2145

72. Aplastic Anemia - Bone Marrow Transplant Center - Rush Cancer Institute Learn about the causes and treatment of aplastic anemia, a deficiency ofred blood cells, white blood cells, and platelets. aplastic anemia. http://www.bone-marrow-transplant.org/cancer-treatment/aplastic-anemia.html

Aplastic Anemia About Aplastic Anemia Aplastic anemia is a rare disease that strikes the bone marrow and produces a deficiency of red blood cells, white blood cells and platelets. Hemorrhages and other life-threatening disorders may accompany aplastic anemia; a bone marrow transplant is the only current effective treatment. Aplastic anemia patients who do not receive a bone marrow transplant may go on to develop myelodysplasia which, in turn, can progress to leukemia Treatment for Aplastic Anemia Although bone marrow transplant is the treatment of choice for aplastic anemia, treatment depends upon the patient's age, the severity of the disease and the availability of a matched donor. Allogeneic transplantation Questions About Aplastic Anemia Q: How common is aplastic amenia? A: Aplastic anemia is a rare disease. It is estimated that there are 2 to 12 new cases per million people per year. It occurs in both adults and children. Myelodysplasia is more common, with the majority of patients being over the age of 50. Q: What are the causes of aplastic anemia?

73. Aplastic Anemia aplastic anemia. Frequently Asked Questions General information. Sourceaplastic anemia MDS International Foundation, Inc. Clinical Trials. http://hml.org/CHIS/topics/aplastic.html

Aplastic Anemia Contents: Informational Sites Clinical Trials Pre-Formulated PubMed Searches Organizations ... Support Groups Informational Sites MEDLINEplus - Anemia Excellent source of authoritative information. Factsheets, organizations, etc. Source: National Library of Medicine Frequently Asked Questions General information. Source: Clinical Trials ClinicalTrials.gov - Aplastic Anemia Clinical studies sponsored primarily by the National Institutes of Health. Source: National Library of Medicine National Institutes of Health Clinical Trials: Aplastic Anemia Industry-sponsored clinical trials. Source: CenterWatch, Inc. Pre-Formulated PubMed Searches These PubMed searches are pre-formulated for your convenience. They should be used as starting points and are not comprehensive. PubMed Aplastic Anemiadiagnosis Also includes pathology, radiography, radionuclide imaging, and ultrasonography. Aplastic Anemiatherapy Organizations This organization concentrates on fighting aplastic anemia, myelodysplastic syndromes, and other bone marrow failure. (Formerly Aplastic Anemia Foundation of America, Inc.) Support Groups For local support groups dealing with this topic, search the

74. Chronic Illness, Children, Aplastic Anemia, Laura Well in March of 1995, I found out that I have this disease called aplastic anemia. Theythink that they might catch aplastic anemia just by being near me. http://www.faculty.fairfield.edu/fleitas/laura.html

When I was in 5th grade, I could barely breathe. Really! If I just walked from the car to the house or any other short distance I had the hardest time catching my breath. People told me that I looked as pale as a ghost, too, which is not the nicest comparison in the world, but I guess they were right. The day I found out what was going on with my body was the day that I woke up with one of my eyes swollen. I didn't feel good at all. I tried to go to school, but since I had a fever and lots of bruises AND a bloody nose that lasted 90 minutes, no lying, I didn't stay very long. Instead I ended up going to the doctor. And then to the hospital! After a lot of medical people tested my blood and my bone marrow, they figured out what was happening to my body. This Sherlock Holmes part was not one bit of fun, believe me! Well in March of 1995, I found out that I have this disease called aplastic anemia. Now I'm an old pro and can tell you all about it. People who have aplastic anemia have bone marrow that just stops working right. Bone marrow is the soft spongy material inside your bones that contains something called stem cells. These are incredibly important little guys that are in charge of making three different types of blood cells. When you don't have normal stem cells, well then you're just out of luck...Your bone marrow doesn't make the red blood cells and the white blood cells and the platelets that you need. Now don't be grossed out. I figured that you'd like to see just what I'm talking about. Here's a picture of your bone marrow, or at least some that probably looks pretty much like yours! See all the stem cells...doing just what they're supposed to do...lucky you!

75. 4anemia.com Living With Anemia Section The causes of aplastic anemia, a condition where the bone marrow fails to producered blood cells, are not always known, but it has been linked to large http://www.4anemia.com/causes_and_types/causes_02_04.htm

Iron-Deficiency Anemia Folic-Acid-Deficiency Anemia Pernicious Anemia Aplastic Anemia ... Hemolytic Anemia The causes of aplastic anemia, a condition where the bone marrow fails to produce red blood cells, are not always known, but it has been linked to large amounts of aspirin, some chronic diseases, radiation, environmental toxins (among them benzene-based compounds and airplane glue), insecticides, and certain drugs (such as chloramphenicol, an antibiotic used only for severe infections such as typhoid fever that cannot be treated with less dangerous drugs). Aplastic anemia is diagnosed with a blood test, which requires a small sample of bone marrow. This is done by inserting a needle into the pelvic/hip bone under local anesthesia. A positive test result will show a significant reduction in volume of all three cell types (red blood cells, white blood cells, platelets). Aplastic anemia is considered a medical emergency and requires hospitalization. There, patients are treated by blood transfusion, antibiotics, and isolation to prevent infection. Other, often experimental, therapies used with some success include cytokines (growth factors) or granulocyte monocyte colony stimulating factor (GM-CSF).

76. Aplastic Anemia & MDS (Myelodysplastic Syndromes) International Foundation, Inc. aplastic anemia MDS (Myelodysplastic Syndromes) International Foundation, Inc. 9found. prev, next. aplastic anemia MDS International Foundation, Inc. http://www.eyemg.com/cgi-bin/aplastic/faq.pl

Frequently Asked Questions advanced search Ask Your Question ... How can I find someone else to talk to? 9 found. prev next P.O. Box 613 Annapolis, Maryland help@aamds.org

77. Aplastic Anemia & MDS (Myelodysplastic Syndromes) International Foundation, Inc. aplastic anemia MDS (Myelodysplastic Syndromes) International Foundation,Inc. aplastic anemia MDS International Foundation, Inc. http://www.eyemg.com/cgi-bin/aplastic/helpful_links.pl

Frequently Asked Questions advanced search Ask Your Question ... Ask the Experts Home Helpful Links BLOOD, PLATELET AND BONE MARROW TRANSPLANTATION Hematopoietic Stem Cells Understanding Your Complete Blood Count America's Blood Centers American Red Cross ... National Marrow Donor Program CLINICAL TRIALS Centerwatch ClinicalTrials.gov Current Controlled Trials Understanding Clinical Trials (NCI) Dictionaries ACOR Cancer Glossary ADAM Medical Encyclopedia CancerWeb Online Medical Dictionary Merriam Webster Medical Dictionary DRUG INFORMATION Buying Drugs Online (FDA) MedlinePlus Drug Information Verified Internet Pharmacy Practice Sites FINANCIAL RESOURCES Centers for Medicare and Medicaid Services Insure Kids Now State Programs Patient Advocate Foundation Pharmaceutical Manufacturers Association (PMA) NATIONAL INSTITUTES OF HEALTH MEDLINEPlus National Cancer Institute (NCI) National Center for Complimentary and Alternative Health (NCCAM) National Heart, Lung and Blood Institute (NHLBI) ... ToxNet PATIENT SUPPORT AA-MDS-TALK Coping with Chronic Illness (pdf) Earl J. Goldberg Aplastic Anemia Foundation (IL) National Family Caregivers Association ... Who's Certified PROFESSIONAL ORGANIZATIONS American Association for Blood Banks American Society of Hematology American Society of Pediatric Hematology/Oncology British Society for Haematology ... National Comprehensive Cancer Network RELATED DISORDERS American Cancer Society Anemia general information Cooley's Anemia Foundation Diamond Blackfan Anemia ... NORD (National Organization of Rare Disorders) P.O. Box 613

78. Christine Jackson - Her Aplastic Anemia Story On May 19 th 1997 Christine was diagnosed with aplastic anemia. The best chancefor a cure for Christine with this disease is a bone marrow transplant. http://www.vlib.com/christine/

On May 19 th 1997 Christine was diagnosed with aplastic anemia . The best chance for a cure for Christine with this disease is a bone marrow transplant. Praise God that her sister Dana is a perfect match and is donating some of her marrow to Christine. Christine's Diary May 97 thru June 97 July 97 August 97 thru June 99 ... Christine's art Christine and the sketch she made minutes after her diagnosis.

79. Aplastic Anemia Facts And Statistics aplastic anemia Facts and Statistics. Background aplastic anemia is a marrow failuresyndrome characterized by peripheral pancytopenia and marrow hypoplasia. http://aplasticcentral.com/Aplastic_Facts/aplastic_facts.htm

Aplastic Anemia Central Holistic Healing Center Aplastic Wheel Research Center ... SPIRIT [ AA FACTS ] AA RESEARCH WHAT'S NEW Holistic Healing Book List ... Contact Bruce Aplastic Anemia Facts and Statistics Sponsors do not influence content. eMedicine Journal Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology Aplastic Anemia Synonyms, Key Words, and Related Terms: progressive hypocythemia, aregeneratory anemia, aleukia hemorrhagica, panmyelophthisis, hypoplastic anemia, toxic paralytic anemia Author Information Introduction Clinical Differentials ... Bibliography AUTHOR INFORMATION Section 1 of 11 Authored by Sameer Bakhshi, MD , Fellow, Department of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Wayne State University Coauthored by Roy Baynes, MB, BCh, PhD, FACP , Charles Martin Professor of Cancer Research, Department of Internal Medicine, Division of Hematology and Oncology, Karmanos Cancer Institute, Wayne State University; Esteban Abella, MD

80. SangStat: Resource Center: Aplastic Anemia aplastic anemia aplastic anemia is a disease in which the stem cellsdisappear from the bone marrow; it primarily affects young people. http://www.sangstat.com/resource/aplastic.asp

Aplastic Anemia Aplastic anemia is a disease in which the stem cells disappear from the bone marrow; it primarily affects young people. Aplastic anemia has a high mortality rate, and even with treatment, quality of life is poor. Patients with this disease are dependent on weekly blood transfusions, which require frequent visits to the physicians' offices and are expensive ($10,000-15,000/year). Both Thymoglobulin and Lymphoglobuline are approved for treatment of aplastic anemia outside of the US, and the majority of sales of Lymphoglobuline in Japan are for the treatment of aplastic anemia.

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