Biological, Medicinal And Pharmaceutical Chemistry clinical Research Scientist/Associate Job Title Experienced clinical ResearchScientist/Associate, medicinal chemistry, clinical research, pharmacology http://chips.csb.ki.se/jobs/bmpch.html
Extractions: Receive email when this page changes other sections in Chemistry Chemistry (generic section) Instrumental Techniques, Analysis and Sensors Molecular Aspects of New Materials Reaction Mechanisms and Dynamics ... Synthesis, New Molecules and Methods Sat, 15 Mar 2003 My Job Alert Title: Scientists Biochemical genomics, clinical development, computational drug discovery, document management, medicinal chemistry, molecular pharmacology, etc. Sat, 8 Mar 2003 My Job Alert Title: Faculty positions Medicinal chemistry and pharmacognosy Sat, 1 Mar 2003 My Job Alert Title: Postdoctoral positions Biological chemistry, cancer biology, cutaneous gene therapy, molecular neurobiology, neurotrophins and function of the spinal cord, etc. Sat, 1 Mar 2003 My Job Alert Title: Assistant/associate professor Medicinal chemistry Wed, 26 Feb 2003 www.chemjobs.net bulletin of job vacancies Job Title : Postdoctoral Research Assistant. Medicinal Chemistry medicinal chemistry Wed, 26 Feb 2003 www.chemjobs.net bulletin of job vacancies Job Title : Post-doctoral Position in Medicinal Chemistry
Journal Titles List: Medicinal Chemistry chemistry, medicinal chemistry and related disciplines Blood Cancer BiochemistryBiophysics Clinica Chimica Acta international journal of clinical chemistry http://www.library.vcu.edu/jbcdocs/cm/source_lists/CMmedchem.html
Medicinal Chemistry Introduction BSc (Hons.) medicinal chemistry will appeal to students with an healthsciences, such as pharmaceutical chemistry, clinical chemistry, and medical http://www.apu.ac.uk/appsci/chemistry/courses/medicinal.htm
Extractions: BSc (Hons.) Medicinal Chemistry will appeal to students with an interest in chemistry in relation to the medical and health sciences, such as pharmaceutical chemistry, clinical chemistry, and medical laboratory science. Students complete a number of core chemistry and biomedical modules and then specialise in modules relating to medicinal aspects of chemistry. Modules available include Clinical Chemistry, Analytical Chemistry, Modern Synthetic Methods, Molecular Cell Biology, Pharmacology . Some of the specialist medicinal modules are delivered at Addenbrookes Hospital in Cambridge. Aims of the course The course aims to provide a comprehensive understanding and appreciation of medicinal and chemical sciences by detailed studies of modules selected from the fields of biology, biomedical sciences and chemistry. The emphasis is firstly on synthesis, structure and analysis of organic molecules and biomolecules and secondly on thweir participation in the metabolism of and interaction with living organisms. Methods of teaching and learning
MEDC 310: Medicinal Chemistry And Drug Design Feb 19, EXAM 1 Moved to Feb 26!!! Feb 19, 24, AT Sneden The medicinal chemistryof Natural Products. 1. chemistry of Metal Species. B. clinical Drugs. http://www.phc.vcu.edu/310/
Extractions: Meetings: MEDC 310 will meet Mondays and Wednesdays at 7:00-8:15 pm in Room 0251 of the new Life Sciences Building. Instructors: Medicinal Chemistry: Dr. D.J. Abraham, Dr. U. Desai, Dr. M. Dukat, Dr. R.A. Glennon, Dr. G.E. Kellogg, Dr. L.B. Kier, Dr. K.A. Reynolds, Dr. J. Rife, Dr. W.H. Soine, Dr. R.B. Westkaemper, Dr. B. Windle and Dr. R. Young Chemistry: Dr. N.P. Farrell and Dr. A.T. Sneden Pharmaceutics: Dr. H.T. Karnes, Dr. M. Sakagami, Dr. M. Sarkar, Dr. J. Venitz and Dr. S. Wu-Pong Dr. Kellogg ( Biotech I, MCV; 828-6452, Glen.Kellogg@vcu.edu ) is the course coordinator. Goals and Objectives: MEDC 310 is designed to expose undergraduate Chemistry, Biology and Pre-medicine majors to the history, theory and practice of Medicinal Chemistry. The course will emphasize a combination of fundamentals and applications of drug design and development. In particular, the molecular aspects of drug action (chemical, physical, and biological) will be discussed. Special emphasis will also be placed on the methods used by Medicinal Chemists to design new drugs to treat significant disease states, and by Pharmaceutical Chemists to develop, deliver and monitor effective therapeutic agents. At the completion of this course: 1. The student should be able to relate basic concepts in a variety of drug classes to their biological action.
Medicinal Chemistry Research in the medicinal chemistry group is principally Until relatively recently,the chemistry and biochemistry of different compounds to clinical trials a http://www.kcl.ac.uk/kis/schools/life_sciences/health/pharmacy/resgrps/mcrg/medc
Extractions: Medicinal Chemistry Group Co-ordinator: Dr S Bansal. Research in the Medicinal Chemistry group is principally concerned with Metallopharmaceuticals and Peptide Pharmaceuticals Until relatively recently, the chemistry and biochemistry of inorganic molecules has been largely ignored by the pharmaceutical industry. Apart from a small number of mainstays, such as ferrous sulphate and desferrioxamine, few metallopharmaceuticals have found application. Recently the climate has changed with the association of critical levels of iron, copper and aluminium with a number of disease states, and characterisation of metalloenzymes. The Department of Pharmacy has considerable expertise in this emerging field. Over the last decade the metallopharmaceuticals group at King's College has brought three different compounds to clinical trials: a 3-hydroxypyridin-4-one for the selective removal of iron; an iron pyrone complex for the treatment of anemia, and a selective phosphate-binding resin for the treatment of hyperphosphatemia. Two of the compounds are now licenced to pharmaceutical companies. The group collaborates closely with several London hospitals and is currently developing orally active compounds for the treatment of thalassaemia, sickle cell anemia and malaria. Other projects associated with the group include the characterisation of non-transferrin-bound iron in various disease states, the use of novel iron-selective fluorophores to image intracellular iron pools and the design of novel antioxidants.
Pharmaceutical And Medicinal Chemistry Fungal Pathogenesis Principles and clinical Applications (Calderone PharmaceuticalChemistry (Bladon), 114.00. Polysaccharides in medicinal Applications (Dumitriu http://www.chipsbooks.com/slipc.htm
Extractions: SUBJECT LIST TITLE LIST ... ONLINE ORDER FORM Pharmaceutical and Medicinal Chemistry TITLE/AUTHOR PRICE Antifungal Azoles (Zirngibl) Antioxidants in Diabetes Management (Packer et al) BioNMR in Drug Research (Zerbe) Capillary Electrophoresis Technology (Guzman) ... Understanding the Process of Aging: The Roles of Mitochondria, Free Radicals, and Antioxidants (Cadenas) Prices subject to change - Prices are in U.S. Dollars Go Back to C.H.I.P.S. Pharmaceutical and Cosmetic Subject List
Extractions: The Mass Spectrometry Group provides analytical support for combinatorial chemistry and for pharmacokinetic and drug metabolism studies on novel compounds in preclinical and early clinical development. The Team provides medicinal chemistry input into the discovery and development of inhibitors of novel molecular targets. Combinatorial Chemistry During the 18 months since the robotic facility for combinatorial synthesis was installed, we have synthesised two medium sized libraries (~1000 compounds in each). From one of these we have identified lead inhibitors of target enzymes histone acetyl transferase and ERK2. We have also developed resin-based methodologies for the synthesis of several further compound libraries.
Faculty of clinical Pharmacy Practice. * Parttime faculty Department of Basic PharmaceuticalSciences. Crider, A. Michael, Ph.D. Professor of medicinal chemistry and http://www.ulm.edu/pharmacy/faculty.htm
Current Medicinal Chemistry Volume 8, Number 14, 2001 Current medicinal chemistry Volume 8, Number 14, 2001. Everninomycin, Glycylcycline,Carbapenem, Lipopeptide and Cephem Antibacterials in clinical Development Pp http://www.bentham.org/cmc/cmc8-14.htm
Extractions: [Back to Contents Page] [Back to Home Page] Current Medicinal Chemistry Volume 8, Number 14, 2001 Contents Antibacterial Drug Development Efflux Pumps: Their Role in Antibacterial Drug Discovery Pp.1699-1711 O. Lomovskaya and W. J. Watkins [Abstract] The Role of Genomics in Antibacterial Target Discovery Pp.1713-1726 Jerry M. Buysse [Abstract] Recent Developments on Ketolides and Macrolides Pp.1727-1758 Yong-Jin Wu and Wei-Guo Su [Abstract] Glycopeptide Derivatives Pp.1759-1773 Adriano Malabarba and Romeo Ciabatti [Abstract] Quinolone, Everninomycin, Glycylcycline, Carbapenem, Lipopeptide and Cephem Antibacterials in Clinical Development Pp.1775-1793 Joanne J. Bronson and John F. Barrett [Abstract] [Back to top] Efflux Pumps: Their Role in Antibacterial Drug Discovery O. Lomovskaya and W. J. Watkins The emergence of active efflux as a major causative factor in antibiotic resistance has been one of the most significant trends in antiinfective chemotherapy over the last decade. The phenomenon affects virtually all classes of antibiotics and frequently results in multi-drug resistant phenotypes. This review analyzes efflux pumps of clinical significance and examines their impact on different antibiotic classes relative to other mechanisms of resistance. Progress in strategies to combat efflux-mediated resistance by modification of existing antibiotics or identification of efflux pump inhibitors is also reviewed. [Back to top] The Role of Genomics in Antibacterial Target Discovery
Current Medicinal Chemistry, Volume 9, No. 20, 2002 Current medicinal chemistry, Volume 9, No. 20, 2002. Abstract. clinical Significanceof Pleiotropic Effects of Statins Lipid Reduction and Beyond Pp.18311850. http://www.bentham.org/cmc/cmc9-20.htm
Extractions: [Back to Contents Page] [Back to Home Page] C urrent Medicinal Chemistry, Volume 9, No. 20, 2002 Contents The Role of CD8+ T Cell Soluble Factors in Human Immunodeficiency Virus Infection Pp.1781-1790 K.F.T. Copeland [Abstract] The Cyanobacterial Origin of Potent Anticancer Agents Originally Isolated from Sea Hares Pp.1791-1806 H. Luesch, G.G. Harrigan, G. Goetz and F.D. Horgen [Abstract] A Review of Chemical Agents in the Pharmacotherapy of Addiction Pp.1807-1818 M.S. Levi and R.F. Borne [Abstract] Reliability of logP Predictions Based on Calculated Molecular Descriptors: A Critical Review Pp.1819-1829 D.Eros, Kövesdi, L.Örfi, K. Takács-Novák, Gy. Acsády and Gy. Kéri [Abstract] Clinical Significance of Pleiotropic Effects of Statins: Lipid Reduction and Beyond Pp.1831-1850 J. Auer, R. Berent, T. Weber and B. Eber [Abstract] [Back to top] The Role of CD8+ T Cell Soluble Factors in Human Immunodeficiency Virus Infection K.F.T. Copeland Cell-mediated immune responses are important for the control of HIV replication in vivo. Cytotoxic CD8+ T cells (CTL) recognize and kill HIV-infected cells which display MHC class-I proteins. In addition to the recognition and killing of infected cells, CD8+T cells can interfere with stages of the HIV life-cycle. Chemokines produced by CD8+ T cells bind to their seven-transmembrane G protein-coupled receptors resulting in a block in the entry of HIV into macrophages and T cells. In addition, activated CD8+ T cells produce factors which strongly modulate HIV at the level of transcription. This review will focus primarily on the current knowledge of the multifactorial functions of CD8+ T cells in HIV infection. An understanding of the mechanisms involved in the CD8-mediated control of transcription may identify other factors with potential value in the treatment of HIV infection.
International Union Of Pure And Applied Chemistry comparison of eight countries (VII.M.2) European Journal of medicinal chemistry,35, pp. 163174, 2000. Properties and units in the clinical laboratory sciences http://sunsite.wits.ac.za/iupac/reports/VII/
Extractions: Department of Medicinal Chemistry Advanced Medicinal Chemistry I Advanced study of organic medicinal agents with emphasis on names, synthesis, chemical properties, and pharmacological properties. Readings in the current literature required. Prerequisite: Consent of the department (3). Advanced Medicinal Chemistry II. Continuation of Medicinal Chemistry 501. Readings in the current literature required. Prerequisite: MEDC 501. (3) Medicinal Chemistry Research Methodology. Lecture and hands-on laboratory in various methods used in medicinal chemistry research. (3) Problems in Medicinal Chemistry. Investigation of individual problems. Prerequisite: Consent of instructor. (1-4,1-4) Seminar on Current Medicinal Chemistry Topics. A seminar consisting of presentations by faculty, graduate students, B.S. Pharmaceutical Science/Medicinal Chemistry track students and invited speakers. (1, 1). Heterocyclic Compounds. Methods of synthesis of medicinally important compounds which contain a heterocyclic ring system. (3)
Gvk Bio - About Us - News & Events company provides a spectrum of services and solutions, in the area of Informatics,medicinal chemistry, Process chemistry and Preclinical development. http://www.gvkbio.com/newssub0.shtml
Extractions: Back gvk bio partners with US drug development company gvk bioSciences Private Limited, has entered into an international partnership with Ricerca, LLC a US drug discovery and development company for small-molecule drug discovery and development. gvk bio will undertake medicinal chemistry and biology services for Ricerca client drug discovery programs and proprietary lead optimization of each company's individual drug targets. The confidence of the global major in gvk bio's capabilities is evident in a statement by Ms. Prabhavati Fernandes, the CEO at Ricerca, "Having access to gvk bio's large pool of skilled chemists, biology capabilities, and state-of-the-art facilities means we can offer better solutions for our discovery clients and more rapidly advance out own discovery and development efforts at the same time," said Ms. Fernandes. Under the terms of the three-year renewable partnership agreement, Ricerca will be the exclusive worldwide partner for access to gvk's medicinal chemistry services. For this purpose, gvk bio will set-up a new facility at the ICICI knowledge park in Hyderabad. Ricerca will provide drug discovery and development guidance to facilitate gvk bio's growth into an international pharmaceutical company with leading edge products of its own. Ricerca will provide gvk bio with some of its proprietary drug targets or early hits for joint drug development. In addition, gvk bio will license its proprietary bioinformatics tools to Ricerca in exchange for access to Ricerca's ADMET and related pharmaceutical data.
Extractions: A B C D E F G H ... Z De novo design - The design of bioactive compounds by incremental construction of a ligand model within a model of the receptor or enzyme active site, the structure of which is known from X-ray or nuclear magnetic resonance (NMR) data. Directed library (also biased- or focused library ) - Library which uses a limited number of building blocks chosen on the basis of pre-existing information or hypothesis which defines the type of functionalities deemed important to obtain a particular activity. For example, every member of the diketopiperazine library shown below contains the thiol pharmacophore known to interact with metalloproteinase enzymes. Distillation - The process of heating a liquid to its boiling point, removing the vapors through a cooling and condensing apparatus, and finally collecting the condensed liquid in a separate receiver. It is commonly used for the separation of two or more liquids in a mixture, or for the separation of the solvent from dissolved substances. Diversity - Some measure of the unrelatedness of a set of, for example, building blocks or members of a combinatorial library.
Astex Appoints Director Of Medicinal Chemistry held the position of Director and Head of the medicinal chemistry Department of ofseveral candidate drugs, which have been progressed to clinical trials, for http://www.noonanrusso.com/news/view_newsitem.aspx?ItemID=405
OUP USA: General Catalog: CLINICAL & MEDICINAL CHEMISTRY clinical medicinal chemistry Enter words or phrases, separated bycommas Continue searching in chemistry k153 k153, Search All http://www.oup-usa.org/k153/catalogs/general/subject/CLINICAL_MEDICINAL_CHEMISTR
OUP USA: General Catalog: BIOLOGICAL CHEMISTRY: BIOLOGICAL chemistry clinical medicinal chemistry Enter words orphrases, separated by commas Continue searching in chemistry http://www.oup-usa.org/k153/catalogs/general/subject/BIOLOGICAL_CHEMISTRY_Clinic
