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Institute of Cancer Research, London, U.K.. Methods in Molecular Biology, Volume 8. Compilation of readily repeatable gene transfer and expression methods from workers expert in the use of a variety of recombinant viral vectors. 36 Contributors, primarily U.K.. ... Read more

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The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates.

This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included.  

There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.  ... Read more

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This volume contains 82 chapters that provide detail and understanding to the fields of human and medical virology. The first section describes general features of common human viruses with specialized chapters related to HIV/AIDS. The volume goes on to describe exotic virus infections, including one now eradicated virus (smallpox) and some now controlled by vaccination such as yellow fever. Concepts of medical virology are further developed with entries on viruses associated with oncogenesis and selections of interest to medical virology.

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Parvovirus B19 is the only parvovirus that has been clearly linked to human diseases. Since its discovery just over 20 years ago, our understanding of B19 at the molecular, cellular, epidemiological and clinical levels has developed rapidly: today the link between B19 and erythema infectiosum, hydrops fetalis, chronic anaemia and transient aplastic crisis is well established. This book provides the reader with comprehensive and detailed reviews of subjects important to understanding parvovirus B19, including the structure and biochemistry of the virus, the clinical and epidemiological features of infection, the diagnosis of infection, the pathophysiology of disease, the host's immune response, and treatment and prevention of disease. Its expert contributions make this publication an essential and timely resource for clinicians, epidemiologists and public health policymakers in their endeavour to optimize treatment and prevention. It will also be appreciated by laboratory researchers interested in the physical and biological properties of the virus and the pathogenesis of B19 disease. ... Read more

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Focuses on the nature and history of viruses and viraldiseases. The methods of stuyding and testing them, and theirclassifications.

Customer Reviews (1)

An excellent introduction to virology
For those who are seeking a basic understanding of virological principles at a biological level, this text provides a readable good basic framework.Topics range from plant and animal viruses, to sub-viral particles to the cellular effects of a viral infection.All in all, an excellent introduction for a new student of virology.

Source: Michael Delander author of Vitamin D Handbook: Structures, Synonyms and Properties. ... Read more

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This volume, derived from Encyclopedia of Virology, provides an overview of the development of virology during the last ten years.  Entries detail the nature, origin, phylogeny and evolution of viruses. It then moves into a summary of our understanding of the structure and assembly of virus particles and describes how this knowledge was obtained. Genetic material of viruses and the different mechanisms used by viruses to infect and replicate in their host cells are highlighted. The volume is rounded out with an overview of some major groups of viruses with particular attention being given to our current knowledge of their molecular biology.

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The successful development of a VZV vaccine reflects intense research interest in this virus over recent years. This comprehensive account of the biology and clinical features of the varicella-zoster virus, published in association with the VZV Research Foundation, surveys current knowledge of the molecular biology, pathogenesis, and clinical features of VZV as the causative agent of chickenpox and zoster (shingles). The volume covers such topics as viral replication, latency, immune mechanisms, epidemiology and disease manifestations, and complications of varicella and zoster. Also included is detailed information on live attenuated varicella vaccine, treatment strategies, and the management of postherpetic pain in zoster patients. As the most authoritative review and guide to the virus and its diseases, this book will appeal to a wide range of clinicians and investigators, including pediatricians, geriatricians, neurologists, dermatologists, infectious disease specialists, and virologists interested in the herpes viruses. ... Read more

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Fundamentals of Plant Virology is an introductory student text covering all of modern plant virology. The author, Dr. R.E.F. Matthews, has written this coursebook based on his classic and comprehensive Plant Virology, Third Edition. Four introductory chapters review properties of viruses and cells and techniques used in their study. Five chapters are devoted to current knowledge of all major plant viruses and related pathogens. Seven chapters describe biological properties such as transmission, host response, disease, ecology, control, classification, and evolution of plant viruses. A historical and future overview concludes the text. Fundamentals of Plant Virology is a carefully designed instructional format for a plant virology course. It is also an invaluable resource for students of plant pathology and plant molecular biology.

Key Features
* Summarizes knowledge on all aspects of plant virology
* Condenses all essential material from Plant Virology 3/e
* Compares basic properties of cells and viruses
* Outlines principles of gene manipulation technology
* Discusses serological techniques including monoclonal antibodies
* Geared to student level course ... Read more

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The present book presents a comprehensive review of Human Herpesvirus-6 (HHV-6) infects up to 90% of the world's population and can cause potentially life-threatening diseases. Clinicians typically do not search for HHV-6, and if they do, they will find only few laboratories providing the necessary diagnostic tests that can differentiate between active and latent infection. Adding to this problem is that scientists still disagree about whether serological or molecular assays will be the best diagnostic test, yet there is no disagreement about the inadequacy of many of thecurrently existing assays. Consequently, our knowledge of etiology and pathogenesis of HHV-6 associated diseases can only come from the combined efforts of clinicians, virologists, molecular biologists and pathologists. It is the prime task of this book to summarize the status quo of HHV-6 research and to further stimulate such a collaboration. It will be a valuable reference for both clinical and basic scientists including epidemiologists, virologists, practicing clinicians and infectiologists, pathologists and essentially all scientists entering the field of herpes virus research. ... Read more

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One hundred years ago, when Martinus W. Beijerinck in Delft and Friedrich Loeffler on Riems Island discovered a new class of infectious agents in plants and animals, a new discipline was born. This book, a compilation of papers written by well-recognized scientists, gives an impression of the early days, the pioneer period and the current state of virology. Recent developments and future perspectives of this discipline are sketched against a historic background. With contributions by A. Alcami, D. Baulcombe, F. Brown, L. W. Enquist, H. Feldmann, A. Garcia-Sastre, D. Griffiths, M. C. Horzinek, A. van Kammen, H.-D. Klenk, F. A. Murphy, T. Muster, R. O'Neill, P. Palese, C. Patience, R. Rott, H.- P. Schmiedebach, S. Schneider-Schaulies, G. L. Smith, J. A. Symons, Y. Takeuchi, V. ter Meulen, P. J. W. Venables, V. E. Volchkov, V. A. Volchkova, R. A. Weiss, W. Wittmann, H. Zheng ... Read more

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(Churchill Livingstone) St. Louis Children's Hospital, MO. Provides practical guidance for those using the clinical laboratory to make specific viral diagnoses. Conventional and molecular techniques are integrated to help the clinician make the best use of all available methods. Includes halftone illustrations and charts. DNLM: Virus Diseases--diagnosis. ... Read more

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Herpes zoster (shingles) is a serious neurocutaneous disease caused by a reactivation of latent varicella-zoster virus (VZV). It has been underestimated in terms of its burden, particularly in the elderly population and in immunocompromised patients, who can develop severe complications such as postherpetic neuralgia, meningitis or optic nerve damage. This book compiles state-of-the-art reviews on herpes zoster and VZV by leading clinicians and researchers in the field. They cover the molecular biology, latency and reactivation of the virus as well as the diagnosis, clinical manifestations, epidemiology and therapy of VZV infection. Infections in high-risk patients (immunocompromised hosts and bone marrow recipients) and pregnant women are considered in detail. Emphasis is also given to the direction of future research efforts which will be focused on the very early prevention of chronic zoster pain by combined antiviral and analgesic therapy, and on the control of herpes zoster by administering a VZV-specific vaccine.Providing a valuable update on current strategies to diagnose, treat and prevent herpes zoster, this book is of special interest to clinical virologists, dermatologists, neurologists, gerontologists, pediatricians, ophthalmologists, otologists and general physicians. ... Read more

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This is the autobiography of Thomas H. Weller, M. D., a research scientist who helped develop the technique of growing viruses in tissue culture, and who became a world leader in the study of tropical diseases.

The development of tissue culture techniques transformed the field of virology. It led to the identification of many new infectious agents...several of which were discovered by Weller...and led to the development of many viral vaccines, starting with the Salk and Sabin vaccines.

In 1954, Weller shared the Nobel Prize in Medicine or Physiology with Drs. John Enders and Frederick Robbins. ... Read more

Customer Reviews (1)

Stellar
Anthony Komaroff's stellar contibution to this work helps it shine.An enjoyable and informative read. ... Read more

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African horse sickness virus is a double-stranded RNA virus which causes a non-contagious, infectious arthropod-borne disease of equines and occasionally dogs. Nine distinct, internationally recognised serotypes of the virus have so far been identified. This book is based upon the findings of two programmes funded by the European Commission. It will be of value not only to the specialist research workers but also to veterinary workers dealing with control and to legislators seeking to promote safe international movement of equines. The topics covered include state-of-the-art discussions on diagnostics, vaccines, molecular biology, vector studies, and epidemiology. ... Read more