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This book reinforces basic subject matter by presenting it in an alternative way and at the same time introduces more advaced material in an attractive format. ... Read more

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Book DescriptioniGenetics: A Mendelian Approach reflects the dynamic nature of modern genetics by emphasizing an experimental, inquiry-based approach with a solid treatment of many research experiments. 1. Genetics: An Introduction, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of Mendelian Genetic Principles, Quantitative Genetics, Gene Mapping in Eukaryotes, Advanced Gene Mapping in Eukaryotes, Variations in Chromosome Structure and Number, Genetics of Bacteria and Bacteriophages, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription, Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Recombinant DNA Technology, Applications of Recombinant DNA Technology, Genomics, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Non-Mendelian Inheritance, Population Genetics, Molecular Evolution For all readers interested in learning the central concepts of genetics. ... Read more

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Abstract: As the Human Genome Project unfolds, more and more genetic disorders are being found that are not transmitted in the usual dominant, recessive, or X-linked pattern. How do you explain these strange exceptions to Mendelian rules to your patients and their families? In this article, Dr Wagstaff discusses imprinting, trinucleotide repeat expansion, mitochondrial inheritance, and mosaicism and explains how they occur and how they affect transmission of inherited diseases. Wagstaff J. Genetics beyond Mendel: understanding nontraditional inheritance patterns. ... Read more

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High Quality Content by WIKIPEDIA articles! Quantitative genetics is the study of continuous traits (such as height or weight) and their underlying mechanisms. It is effectively an extension of simple Mendelian inheritance in that the combined effect of the many underlying genes results in a continuous distribution of phenotypic values. The field was founded, in evolutionary terms, by the originators of the modern synthesis, R.A. Fisher, Sewall Wright and J. B. S. Haldane, and aimed to predict the response to selection given data on the phenotype and relationships of individuals.Analysis of Quantitative Trait Loci, or QTL, is a more recent addition to the study of quantitative genetics. A QTL is a region in the genome that affects the trait or traits of interest. Quantitative trait loci approaches require accurate phenotypic, pedigree and genotypic data from a large number of individuals. ... Read more

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High Quality Content by WIKIPEDIA articles! Thomas Hunt Morgan (September 25, 1866 ? December 4, 1945) was an American geneticist and embryologist. Morgan received his PhD from Johns Hopkins University in 1890 and researched embryology during his tenure at Bryn Mawr. Following the rediscovery of Mendelian inheritance in 1900, Morgan's research moved to the study of mutation in the fruit fly Drosophila melanogaster. In his famous Fly Room at Columbia University Morgan was able to demonstrate that genes are carried on chromosomes and are the mechanical basis of heredity. These discoveries formed the basis of the modern science of genetics. When he was awarded the Nobel Prize in Physiology or Medicine in 1933 he was the first person awarded the Prize in genetics, for his discoveries concerning the role played by the chromosome in heredity. ... Read more

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High Quality Content by WIKIPEDIA articles! The Punnett square is a diagram that is used to predict an outcome of a particular cross or breeding experiment. It is named after Reginald C. Punnett, who devised the approach, and is used by biologists to determine the probability of an offspring having a particular genotype. The Punnett square is a summary of every possible combination of one maternal allele with one paternal allele for each gene being studied in the cross. In this example, both organisms have the genotype Bb. They can produce gametes that contain either the B or b allele. (It is conventional in genetics to use capital letters to indicate dominant alleles and lower-case letters to indicate recessive alleles.) The probability of an individual offspring having the genotype BB is 25%, Bb is 50%, and bb is 25%. ... Read more

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Autism has a strong genetic basis, although the genetics of autism is complex and it is unclear whether ASD is explained more by multigene interactions or by rare mutations with major effects. Early studies of twins estimated the heritability of autism to be more than 90%; in other words, that 90% of the differences between autistic and non-autistic individuals is due to genetic effects. This may be an overestimate; new twin data and models with structural genetic variation are needed. When only one identical twin is autistic, the other often has learning or social disabilities. For adult siblings, the risk of having one or more features of the broader autism phenotype might be as high as 30%, much higher than the risk in controls. Genetic linkage analysis has been inconclusive; many association analyses have had inadequate power. For each autistic individual, mutations in more than one gene may be implicated. Mutations in different sets of genes may be involved in different autistic individuals. ... Read more

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Human mitochondrial genetics is the study of the genetics of the DNA contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mother's ovum. The mitochondrial DNA inherited by a female from its mother's egg produces mitochondria to supply the energy to sustain the female's eggs. ... Read more

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Human mitochondrial genetics is the study of the genetics of the DNA contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mother's ovum. The mitochondrial DNA inherited by a female from its mother's egg produces mitochondria to supply the energy to sustain the female's eggs. Mitochondrial inheritance is therefore non-Mendelian, as Mendelian inheritance presumes that half the genetic material of a fertilized egg (zygote) derives from each parent. ... Read more

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Gregor Johann Mendel (July 20, 1822? January 6, 1884) was an Augustinian priest and scientist, who gained posthumous fame as the figurehead of the new science of genetics for his study of the inheritance of certain traits in pea plants. Mendel showed that the inheritance of these traits follows particular laws, which were later named after him. The significance of Mendel's work was not recognized until the turn of the 20th century. The independent rediscovery of these laws formed the foundation of the modern science of genetics. ... Read more

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This laboratory manual is best known for its ability to help students develop critical and creative reasoning skills in investigating science. Dr. Mader provides step-by-step procedures and hands-on activities to help students learn the concepts of biology.This manual covers the entire field of general biology.

This manual is color customizable so that instructors can build a manual to fit the way they teach their course. ... Read more

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The text was brand new and a great savings over the college book store price. Came quickly. ... Read more

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High Quality Content by WIKIPEDIA articles! Thomas Hunt Morgan (September 25, 1866 ? December 4, 1945) was an American geneticist and embryologist. Morgan received his PhD from Johns Hopkins University in 1890 and researched embryology during his tenure at Bryn Mawr. Following the rediscovery of Mendelian inheritance in 1900, Morgan's research moved to the study of mutation in the fruit fly Drosophila melanogaster. In his famous Fly Room at Columbia University Morgan was able to demonstrate that genes are carried on chromosomes and are the mechanical basis of heredity. ... Read more